74666-9
Monoclonal band observed [Identifier] in Urine by Immunofixation
Active
Term Description
Monoclonal Protein Peak 1 Identification in Urine by Immunofixation (IFE).
Source: Regenstrief LOINC
Part Descriptions
LP18363-9 Monoclonal band observed
A monoclonal band (M-spike, monoclonal protein isotype) is often found in patients with monoclonal gammopathies. Following protein electrophoresis, immunofixation is used to identify the immunoglobulin heavy chain and/or light chain. Monoclonal peaks greater than 3 g/dL and IgG or IgA are seen in patients with Multiple Myeloma (MM). A monoclonal peak greater than 3 g/dL and IgM is seen in patients with macroglobulinemia. An alternate methodology for identifying the monoclonal protein isotype is MALDI-TOF, in which known information regarding the unique mass of each isotype is used to determine and quantify the isotype present in the patient sample based on the mass spectra generated from the sample.
Source: Regenstrief LOINC
LP6336-4 Immunofixation
Plasma or concentrated urine is deposited on a gel. With an electrical current the proteins are sorted in function of their size, after which antigens for each targeted type of immunoglobulin are deposited on the gel. Thus more or less narrow bands appear on the gel, marking the location of the various immunoglobulines.
Immunofixation tends to replace protein electrophoresis because:
• it is faster (results within three hours);
• it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
• it can be partially automated and can be used in more laboratories;
• it is more easily read and interpreted.
Immunofixation is however only sensitive to immunoglobulins and is more expensive than protein electrophoresis.
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Source: Wikipedia, Immunofixation
Fully-Specified Name
- Component
- Monoclonal band observed
- Property
- Prid
- Time
- Pt
- System
- Urine
- Scale
- Nom
- Method
- Immunofixation
Additional Names
- Short Name
- Monoclon Band Obs Ur IFE
- Display Name
- Monoclonal band observed Immunofixation Nom (U)
- Consumer Name Alpha Get Info
- Monoclonal band observed, Urine
Example Answer List: LL2432-4
Source: Regenstrief LOINCAnswer | Code | Score | Answer ID |
---|---|---|---|
Kappa | LA19741-0 | ||
Lambda | LA19742-8 |
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.48
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9441
Member of these Panels
LOINC | Long Common Name |
---|---|
101909-0 | Protein monoclonal panel - Urine |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Banda monoclonal observada: |
es-MX | Spanish (Mexico) | Banda monoclonal observada: |
fr-CA | French (Canada) | Bande monoclonale: |
fr-FR | French (France) | Bandes monoclonales observées: |
fr-BE | French (Belgium) | Bande monoclonale: Synonyms: Présence de bande monoclonale |
it-IT | Italian (Italy) | Banda monoclonale osservata: Synonyms: Chimica Presenza o Identità Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | monoclonale band waargenomen: |
pt-BR | Portuguese (Brazil) | Banda monoclonal observada: |
ru-RU | Russian (Russian Federation) | Моноклональная полоса наблюдённая: Synonyms: Номинальный; |
tr-TR | Turkish (Turkey) | Monoklonal band, gözlenen: |
zh-CN | Chinese (China) | 已观察到的单克隆区带: Synonyms: IFE; |
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