74828-5

Snowshoe hare virus neutralizing antibody [Presence] in Serum by Neutralization test

Active

Part Descriptions

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP21136-4 Snowshoe hare virus
A member of the California group of arboviruses (family bunyaviridae) causing fever, severe headache, and nausea in humans in North America. Copyright Copyright © Biology-Online.org. All Rights Reserved. Source: Biology Online, Snowshoe hare virus

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Snowshoe hare virus Ab.Neut:PrThr:Pt:Ser:Ord:Neut
Long Common Name: Snowshoe hare virus neutralizing antibody [Presence] in Serum by Neutralization test
Short Name: SSHV NAb Ser Ql Nt
Display Name: Snowshoe hare virus neut ab Neut test Ql (S)
Consumer Name Alpha Get Info: Snowshoe Hare virus neutralizing antibody, Blood

Part Model Get Info

Component
Snowshoe hare virus Ab.Neut
LP430473-1
- Analyte
  Snowshoe hare virus Ab.Neut
  LP430473-1
  - Component Numerator
    Snowshoe hare virus Ab.Neut
    LP430473-1
    - Component Numerator Core
      Snowshoe hare virus
      LP21136-4
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Neut
LP6416-4

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.48
Last Updated: Version 2.72 (NAM)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Snowshoe hare virus (SSHV) Ab.neutralizační:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Neutralizační test
el-GR	Greek (Greece)	Ιός Snowshoe hare Ab.Neut:PrThr:Pt:Ορός:Ord:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Ord PrThr Pt Αντίσωμα Ιός Ιός Snowshoe hare Ορός Ουδετερόφιλα
es-ES	Spanish (Spain)	Virus de la liebre de requeta Anticuerpos antineutrófilos:PrThr:Punto temporal:Suero:Ord:Prueba de neutralización
es-MX	Spanish (Mexico)	Virus de la liebre de raquetas de nieve Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Prueba de neutralización
fr-FR	French (France)	Virus du lièvre des neiges Ac neutralisant:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Neutralisation
fr-CA	French (Canada)	Virus lièvre américain Ac.neut:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Test de neutralisation
it-IT	Italian (Italy)	Lepre scarpa da neve, virus Ab.Neut:PrThr:Pt:Siero:Ord:Neut Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus della lepre scarpa da neve
nl-NL	Dutch (Netherlands)	Snowshoe hare-virus As.neutraliserend:aanwezigheid:moment:serum:ordinaal:neutralisatietest Synonyms: antistof; antilichaam Snowshoe hare virus
pl-PL	Polish (Poland)	Wirus Snowshoe hare Ab.Neutralizujące:granica wykrywalności:punkt w czasie:surowica:uporządkowany:test neutralizacji Synonyms: Przeciwciała do wirusa Snowshoe hare Przeciwciała neutralizujące do wirusa Snowshoe hare
pt-BR	Portuguese (Brazil)	Lebre Snowshoe vírus Ac:Limiar:Pt:Soro:Ord:
zh-CN	Chinese (China)	雪鞋野兔病毒抗体.中和:存在情况或阈值:时间点:血清:序数型:中和试验 Synonyms: Ab;自身抗体 SSHV Ab SSHV 抗体 SSHV;雪兔病毒;雪鞋兔病毒;雪鞋野兔病毒 (Snowshoe hare virus);雪鞋野兔病毒（Snowshoe hare virus，SSHV）中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间雪兔病毒 Ab 雪兔病毒抗体雪鞋兔病毒 Ab 雪鞋兔病毒抗体雪鞋野兔病毒 (Snowshoe hare virus) Ab 雪鞋野兔病毒 (Snowshoe hare virus) 抗体雪鞋野兔病毒 Ab

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.