Version 2.73

74888-9Sterols panel [Moles/volume] - Serum or PlasmaActive

Term Descriptions

Determination of sterols (e.g. desmosterol, lathosterol, campesterol, and sitosterol) in serum or plasma is performed to diagnose conditions such as desmosterolosis (desmosterol reductase deficiency) and sitosterolemia. Patients with sitosterolemia are known to develop premature coronary artery disease, cerebrotendinous xanthomatosis (CTX), and Smith-Lemli-Optiz (SLO) syndrome. is performed to assess dietary plant sterol intake and intestinal absorption.
Source: Regenstrief LOINC

Phytosterols (e.g., β-sitosterol, campesterol, stigmasterol, and brassicasterol) are common components of plant foods,such as vegetable oils, seeds, and nuts. An average Western diet contains approx. 200-400 mg of phytosterols per day. Phytosterols are structurally similar to cholesterol and differ only in the number of carbons or double bonds in the side chain. Since serum and tissue phytosterols are derived from intestinal absorption, levels reflect dietary plant sterol intake and intestinal absorption. Markedly increased serum phytosterol concentrations (e.g., β-sitosterol > 50 mg/l) is seen in sitosterolemia, a rare autosomal recessive lipid disorder. These patients develop premature coronary heart disease. A study suggests that even slightly increased campesterol (3.8 ± 1.6 mg/l) and β-sitosterol (3.1 ± 1.1 mg/l) concentrations in serum may contribute to the risk of coronary heart disease.[PMID:15489546]
Source: Regenstrief LOINC, PMID:15489546

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
74888-9 Sterols panel [Moles/volume] - Serum or Plasma
Indent74907-7 Beta sitosterol [Moles/volume] in Serum or Plasma pmol/L
Indent77371-3 Brassicasterol [Moles/volume] in Serum or Plasma pmol/L
Indent58464-9 Campesterol [Moles/volume] in Serum or Plasma umol/L
Indent74432-6 Cholestanol [Moles/volume] in Serum or Plasma umol/L
Indent14647-2 Cholesterol [Moles/volume] in Serum or Plasma mmol/L
Indent74433-4 Cholestanol/Cholesterol in Serum or Plasma %
Indent32289-1 7-Dehydrocholesterol [Moles/volume] in Serum or Plasma umol/L
Indent56535-8 8-Dehydrocholesterol [Moles/volume] in Serum or Plasma umol/L
Indent74905-1 Desmosterol [Moles/volume] in Serum or Plasma pmol/L
Indent74898-8 Lanosterol [Moles/volume] in Serum or Plasma pmol/L
Indent77373-9 Lathosterol [Moles/volume] in Serum or Plasma pmol/L
Indent74887-1 Stigmastanol [Moles/volume] in Serum or Plasma pmol/L
Indent74886-3 Stigmasterol [Moles/volume] in Serum or Plasma pmol/L

Fully-Specified Name

Sterols panel

Additional Names

Short Name
Sterols Pnl SerPl-sCnc
Display Name
Sterols panel [Moles/Vol]
Consumer Name Alpha
Sterols panel, Blood

Basic Attributes

First Released
Version 2.48
Last Updated
Version 2.50
Change Reason
Changed Component name from Phytosterols to Sterols since panel includes both sterols and phytosterols.
Order vs. Observation
Panel Type

Member of these Groups

LG46763-5 Sterols panel|Pt|Ser/Plas

Language Variants Get Info

zh-CNChinese (China)
nl-NLDutch (Netherlands)
sterolen panel:mol/volume:moment:serum of plasma:-:
fr-FRFrench (France)
Stéroïdes panel:Moles/Volume:Ponctuel:Sérum/Plasma:-:
it-ITItalian (Italy)
Steroli, panel:SCnc:Pt:Siero/Plasma:-:
pt-BRPortuguese (Brazil)
Fitosterois painel::Pt:Soro/Plas:-:
ru-RURussian (Russian Federation)
Фитостеролы панель:МолКонц:ТчкВрм:Сыв/Плаз:-:
es-MXSpanish (Mexico)
Panel de esteroles:Concentración de sustancias:Punto temporal:Suero o Plasma:-:
es-ESSpanish (Spain)
Fitosteroles:Concentración de sustancia:Punto temporal:Suero o Plasma:-:

LOINC FHIR® API Example - CodeSystem and Questionnaire Requests Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74888-9 https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/74888-9