74912-7

Primidone [Mass/volume] in Serum or Plasma --trough

Active

Part Descriptions

LP14730-3 Primidone
Primidone is an anticonvulsant of the pyrimidinedione[4] class, the active metabolites of which, phenobarbital (major) and phenylethylmalonamide (PEMA) (minor), are also anticonvulsants. It is used mainly to treat complex partial, simple partial, generalized tonic-clonic seizures, myoclonic, and akinetic seizures and has been a valuable alternative to propranolol in the treatment of essential tremor. Unlike other anticonvulsants such as carbamazepine and valproic acid, primidone is rarely used in the treatment of bipolar disorder or any other psychiatric problem. It is also not widely used in treatment of neuropathic pain, trigeminal neuralgia, migraine. Primidone has been occasionally used to treat long QT syndrome, cerebral palsy, and athetosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Primidone (Wikipedia)

LP14730-3 Primidone
Primidone (2-desoxyphenobarbitone, brand name Mysoline®) is an antiepileptic drug used to treat complex partial and generalized tonic-clonic seizures. It is converted to phenylethylmalonamide (PEMA) and phenobarbitone. PMID: 7104185 Source: Regenstrief LOINC

LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

LOINC Names Get Info

Fully-Specified Name: Primidone^trough:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: Primidone [Mass/volume] in Serum or Plasma --trough
Short Name: Primidone Trough SerPl-mCnc
Display Name: Primidone trough [Mass/Vol]
Consumer Name Alpha Get Info: Primidone trough, Blood

Part Model Get Info

Component
Primidone^trough
LP308010-0
- Analyte
  Primidone
  LP14730-3
  - Component Numerator
    Primidone
    LP14730-3
    - Component Numerator Core
      Primidone
      LP14730-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  trough
  LP20176-1
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.48
Last Updated: Version 2.48 (MIN)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
78436-3	Primidone and PHENobarbital trough panel - Serum or Plasma

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Primidon^Údolní koncentrace:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Πριμιδόνη^ελάχιστα επίπεδα:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX MCnc Pt Qn ελάχιστα επίπεδα Ορός Ορός/Πλάσμα Πλάσμα Πριμιδόνη
es-ES	Spanish (Spain)	Primidona^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Primidona ^ canal:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	Primidoon^baas:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Primidone^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Primidone^taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Primidone^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif: Synonyms: Minimum, nadir
it-IT	Italian (Italy)	Primidone^valore minimo:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL	Dutch (Netherlands)	primidon^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
ru-RU	Russian (Russian Federation)	Примидон^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Primidon^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant: Synonyms: çukur düzey
zh-CN	Chinese (China)	扑米酮^波谷:质量浓度:时间点:血清/血浆:定量型: Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量去氧苯巴比妥;扑痫酮;普奈米东;普里米酮;麦苏林可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆

Example Units

Unit	Source
mg/L	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74912-7

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.