74913-5
Deprecated Escitalopram [Mass/volume] in Serum or Plasma --trough
Deprecated
Status Information
- Status
- DEPRECATED
- Comment
- A drug level for this drug is typically not done as a trough level, i.e., the specimen does not have to be drawn just before the next dose.
| Map-To | Long Common Name | Mapping Guidance |
|---|---|---|
| 34405-1 | Escitalopram [Mass/volume] in Serum or Plasma |
Part Descriptions
LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Trough levels for therapeutic drug monitoring
LP31801-1 Escitalopram
Escitalopram (trade names Lexapro, Cipralex, Seroplex, Lexamil) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class with a half life of 27-32 hours. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment in adults with major depressive disorder, generalized anxiety disorder, social anxiety disorder , or panic disorder. Escitalopram is the S-stereoisomer (enantiomer) of the earlier Lundbeck drug citalopram, hence the name escitalopram. Escitalopram is noted for its high selectivity of serotonin reuptake inhibition and has side effects typical for the SSRI class. Testing for this drug and its major metabolite, norescitalopram, is performed to monitor drug doses. Excessive doses of escitalopram usually cause relatively minor untoward effects such as agitation and tachycardia. However, dyskinesia, hypertonia and clonus may occur in some cases. Plasma escitalopram concentrations are usually in a range of 20-80 μg/L in therapeutic situations and may reach 80-200 μg/L in the elderly, patients with hepatic dysfunction, those who are poor CYP2C19 metabolizers or following acute overdose.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Escitalopram
LOINC Names Get Info
- Fully-Specified Name
- Escitalopram^trough:
MCnc: Pt: Ser/Plas: Qn: - Long Common Name
- Deprecated Escitalopram [Mass/volume] in Serum or Plasma --trough
- Short Name
- Deprecated Escitalopram Trough SerPl-mCn
- Display Name
- Escitalopram trough [Mass/Vol]
- Consumer Name Alpha Get Info
- Escitalopram trough, Blood
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.48
- Last Updated
- Version 2.54 (DEL)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Escitalopram^Údolní koncentrace: |
| el-GR | Greek (Greece) | Εσκιταλοπράμη^ελάχιστα επίπεδα: Synonyms: DRUG/TOX MCnc Pt Qn ελάχιστα επίπεδα Εσκιταλοπράμη Ορός Ορός/Πλάσμα Πλάσμα |
| es-ES | Spanish (Spain) | Escitalopram^Valle monitorización terapéutica de fármacos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Escitalopram ^ a través: |
| et-EE | Estonian (Estonia) | Estsitalopraam^baas: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Escitalopram^Creux: |
| fr-BE | French (Belgium) | Escitalopram^Creux: Synonyms: Minimum, nadir |
| fr-FR | French (France) | Escitalopram^taux résiduel: |
| it-IT | Italian (Italy) | Escitalopram^valore minimo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM |
| nl-NL | Dutch (Netherlands) | escitalopram^dalspiegel: |
| ru-RU | Russian (Russian Federation) | Эсциталопрам^остаточная концентрация: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Eskitalopram^en düşük: Synonyms: çukur düzey |
| zh-CN | Chinese (China) | 右旋西酞普兰^波谷: Synonyms: 一剂药物的初始剂量; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
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LOINC Copyright
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