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Status Information

Status
DEPRECATED
Comment
Trough levels are based on parent drug and not the metabolite.
Map-ToLong Common NameMapping Guidance
34415-0Normirtazapine [Mass/volume] in Serum or Plasma

Part Descriptions

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

LP31803-7   Normirtazapine
Mirtazapine (Remeron, Avanza, Zispin, Reflex) is a tetracyclic antidepressant (TeCA) used primarily in the treatment of depression. Mirtazapine is also sometimes used as an anxiolytic, hypnotic, antiemetic, appetite stimulant, and antihistamine, among other indications. Along with its close analogues mianserin and setiptiline, mirtazapine is one of the few noradrenergic and specific serotonergic antidepressants (NaSSAs). Mirtazapine and its N-demethyl metabolite, normirtazapine, can be detected in specimens by various methods, including high performance liquid chromatography (HPLC). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mirtazapine

LP31803-7   Normirtazapine
Mirtazapine is metabolized by N-demethylation to normirtazapine, which is thought to account for 5-10% of total activity of the parent compound. Normirtazapine accumulates with chronic treatment. Measurement of Mirtazapine and Normirtazapine in plasma, hair and other specimens are useful for assessing compliance and in diagnosis of acute poisoning. Source: Regenstrief LOINC, PMID: 14643499

LOINC Names Get Info

Fully-Specified Name
Normirtazapine^trough:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Deprecated Normirtazapine [Mass/volume] in Serum or Plasma --trough
Short Name
Deprecated Normirtazapine Trough SerPl-m
Display Name
Normirtazapine trough [Mass/Vol]
Consumer Name Alpha Get Info
Normirtazapine trough, Blood

Part Model Get Info

  • Component
    Normirtazapine^trough
    LP307989-6
    • Analyte
      Normirtazapine
      LP31803-7
      • Component Numerator
        Normirtazapine
        LP31803-7
        • Component Numerator Core
          Normirtazapine
          LP31803-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      trough
      LP20176-1
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.54 (DEL)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Normirtazapin^Údolní koncentrace:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Νορμιρταζαπίνη^ελάχιστα επίπεδα:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: DRUG/TOX MCnc Pt Qn ελάχιστα επίπεδα Νορμιρταζαπίνη Ορός Ορός/Πλάσμα Πλάσμα
es-ESSpanish (Spain)Nomirtazapine^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Normirtazapina ^ a través:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EEEstonian (Estonia)Normirtatsapiin^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CAFrench (Canada)Normirtazapine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-BEFrench (Belgium)Normirtazapine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
fr-FRFrench (France)Normirtazapine^taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)Normirtazapina^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NLDutch (Netherlands)normirtazapine^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
ru-RURussian (Russian Federation)Нормиртазапин^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Normirtazapin^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CNChinese (China)去甲基米氮平^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 脱甲基米氮平;去甲米氮平;去甲基瑞美隆;瑞美隆代谢产物;米氮平代谢产物 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

UnitSource
ug/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74946-5