75212-1

Malonylcarnitine (C3-DC)/Decanoylcarnitine (C10) [Molar ratio] in DBS

Active

Term Description

C3DC (Malonylcarnitine)/C10 (Decanoylcarnitine) is a marker for malonic acidemia (also known as malonic aciduria), which is one of the secondary conditions on the HHS Secretary's Recommended Uniform Screening Panel for newborn screening.

Part Descriptions

LP70167-9 Decanoylcarnitine (C10)
Decanoylcarnitine is a primary marker for Medium-chain acyl-CoA dehydrogenase deficiency and Glutaric acidemia type II. Secondary marker for Medium-chain ketoacyl-CoA thiolase deficiency. Source: Regenstrief LOINC

LP70363-4 Malonylcarnitine (C3-DC)
Malonylcarnitine is a metabolite that accumulates with specific disruption of fatty-acid oxidation caused by impaired entry of long-chain acylcarnitine esters into the mitochondria and failure of the mitochondrial respiratory chain at complex 11 and malonyl-CoA decarboxylase (EC 4.1.1.9) deficiency [OMIM: 248360]. Malonylcarnitine has also been found to accumulate in some newborns with medium-chain acyl-CoA dehydrogenase (EC 1.3.99.3) deficiency [OMIM: 201450], PMID: 11558490, PMID: 15303003, PMID: 12651823. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Malonylcarnitine

LOINC Names Get Info

Fully-Specified Name: Malonylcarnitine (C3-DC)/Decanoylcarnitine (C10):SRto:Pt:Bld.dot:Qn:
Long Common Name: Malonylcarnitine (C3-DC)/Decanoylcarnitine (C10) [Molar ratio] in DBS
Short Name: Malonylcarn/C10 DBS-sRto
Display Name: C3-DC/Decanoylcarnitine (C10) (DBS) [Molar ratio]
Consumer Name Alpha Get Info: C3-DC/Decanoylcarnitine (C10), Dried blood spot

Part Model Get Info

Component
Malonylcarnitine (C3-DC)/Decanoylcarnitine (C10)
LP286468-6
- Analyte
  Malonylcarnitine (C3-DC)/Decanoylcarnitine (C10)
  LP286468-6
  - Component Numerator
    Malonylcarnitine (C3-DC)
    LP70363-4
    - Component Numerator Core
      Malonylcarnitine (C3-DC)
      LP70363-4
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Decanoylcarnitine (C10)
    LP70167-9
    - Component Denominator Core
      Decanoylcarnitine (C10)
      LP70167-9
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld.dot
LP21304-8
- System Core
  Bld.dot
  LP21304-8
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.48
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 18573

Member of these Panels

LOINC	Long Common Name
58092-8	Acylcarnitine newborn screen panel
54089-8	Newborn screening panel American Health Information Community (AHIC)

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Malonylkarnitin (C3-DC)/dekanoylkarnitin (C10):Látkový poměr:Časový bod:Suchá krevní kapka (DBS):Kvantitativní:
el-GR	Greek (Greece)	Μηλονυλοκαρνιτίνη (C3-DC)/Δεκανοϋλοκαρνιτίνη (C10):SRto:Pt:Bld.dot:Qn: Synonyms: Bld.dot CHEM Pt Qn SRto Αίμα Δεκανοϋλοκαρνιτίνη (C10) Μηλονυλοκαρνιτίνη (C3-DC)
es-ES	Spanish (Spain)	Malonilcarnitina (C3-DC)/Decanoilcarnitina (C10):Relacion de Sustancia:Punto temporal:gota de sangre (papel de filtro):Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Malonilcarnitina (C3-DC) / Decanoilcarnitina (C10):Proporción de sustancia:Punto temporal:DBS:Cuantitativo:
fr-CA	French (Canada)	Malonylcarnitine (C3-DC)/Décanoylcarnitine (C10):Ratio de substance:Temps ponctuel:Sang sur papier filtre:Quantitatif:
fr-FR	French (France)	Malonylcarnitine (C3-DC)/décanoylcarnitine (C10):Moles ratio:Ponctuel:Sang buvard:Numérique:
fr-BE	French (Belgium)	Malonylcarnitine (C3-DC)/Décanoylcarnitine (C10):Ratio de substance:Temps ponctuel:Sang sur papier filtre:Quantitatif:
it-IT	Italian (Italy)	Malonilcarnitina (C3-DC)/Decanoilcarnitina (C10):Srto:Pt:Sangue.su carta da filtro:Qn: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza Sangue Spot sangue secco
nl-NL	Dutch (Netherlands)	malonylcarnitine (C3-DC)/decanoylcarnitine (C10):molaire verhouding:moment:gedroogde bloedspot:kwantitatief:
pl-PL	Polish (Poland)	Malonylokarnityna (C3-DC)/dekanoilokarnityna (C10):współczynnik molowy:punkt w czasie:sucha kropla krwi:ilościowy:
ru-RU	Russian (Russian Federation)	Малонилкарнитин (C3-DC)/Деканоилкарнитин (C10):МольОтн:ТчкВрм:Кр.Сух.капл:Колич: Synonyms: Количественный Кровь Кровь сухая капля Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR	Turkish (Turkey)	Malonilkarnitin (C3-DC)/Dekanoilkarnitin (C10):SOrn:Zmlı:Kan.nokta:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	丙二酰肉碱 (C3-DC)/癸酰肉碱 (C10):物质的量比率:时间点:全血.斑点:定量型: Synonyms: 丙二酰肉碱（肉毒碱、三甲基羟基丁酰甜菜碱、卡尼丁） (C3-DC);C3DC;C3-DC;C3-DCC;丙二酸单酰肉碱;丙二酰基肉碱;丙二酰基酰基肉碱;丙二酸单酰基肉碱;丙二酸单酰肉碱, C3-DC;酰基肉碱丙二酸单酰基;丙二酸单酰肉碱;丙二酰肉碱全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值癸酰肉碱（肉毒碱、三甲基羟基丁酰甜菜碱、卡尼丁） (C10);C10 癸酰肉碱（肉毒碱、三甲基羟基丁酰甜菜碱、卡尼丁） (C10);C10;癸酰基肉碱;癸酰肉碱, C10 血;血液

Example Units

Unit	Source
{ratio}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.