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Term Description

Antibody screening is used to demonstrate unexpected antibodies (other than ABO) and is performed on both donors and recipients to help ensure compatibility between recipient antibodies and donor red cells. Low ionic strength saline (LISS) is a blood banking potentiating agent that works by decreasing the repelling charges between red cells (zeta potential), thus packing the reds cells closer together for increased antibody bridging. This then decreases the incubation time for the sensitization phase in the antibody screening. A downside to using LISS is that it enhances the expression of cold antibodies and auto-antibodies that may not be significant. In addition, the ratio of serum to red cells must be adhered to strictly to maintain the ionic strength of the mixture. If ionic strength is too high, false negatives may occur, and if it is too low, false positives due to complement binding may occur.

LOINC Names Get Info

Fully-Specified Name
Blood group antibody:PrThr:Pt:Ser/Plas:Ord:Blood group antibody screen.LISS
Long Common Name
Blood group antibody screen [Presence] in Serum or Plasma by Low ionic strength saline (LISS)
Short Name
Bld gp Ab Scn SerPl Ql LISS
Display Name
Blood group antibody screen LISS Ql
Consumer Name Alpha Get Info
Blood group antibody screen, Blood

Part Model Get Info

  • Component
    Blood group antibody
    LP444338-0
    • Analyte
      Blood group antibody
      LP444338-0
      • Component Numerator
        Blood group antibody
        LP444338-0
        • Component Numerator Core
          Blood group antibody
          LP444338-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Blood group antibody screen.LISS
    LP444332-3

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
BLDBK
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: Screen should be omitted from Component. It should be in Method.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
2564

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Krevní skupina protilátky screening:Přítomnost nebo práh:Časový bod:Sérum/plazma:Ordinální:Hypotonický pufrovaný roztok (LISS)
es-ESSpanish (Spain)Prueba de detección de anticuerpos del grupo sanguíneo:PrThr:Punto temporal:Suero o Plasma:Ord:Cribado de anticuerpos del grupo sanguíneo. Método LISS
Synonyms: Cribado de anticuerpos del grupo sanguíneo. Método LISS (solución de baja fuerza iónica) Prueba de detección de anticuerpos contra antígenos de los hematíes
es-MXSpanish (Mexico)Examen de anticuerpos del grupo sanguíneo:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Solución salina de baja fuerza iónica (LISS)
fr-FRFrench (France)Anticorps anti-érythrocytaires:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Dépistage anticorps anti-érythrocytaires LISS
fr-CAFrench (Canada)Anticorps des groupes sanguins:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Anticorps des groupes sanguins dépistage.Salin hypotonique
it-ITItalian (Italy)Gruppo sanguigno,anticorpo:PrThr:Pt:Siero/Plasma:Ord:Gruppo sanguigno, screening anticorpo.LISS
Synonyms: Banca del sangue Gruppo sanguigno,screening anticorpo Plasma Presenza o Soglia Punto nel tempo (episodio) Screening anticorpo del guppo sanguigno Screening tossicologico Siero Siero o Plasma Soluzione a bassa forza ionica (LISS) Soluzione salina a bassa forza ionica (LISS)
nl-NLDutch (Netherlands)bloedgroep antistofscreening:aanwezigheid:moment:serum of plasma:ordinaal:zoutoplossing met lage ionsterkte (LISS)
Synonyms: LISS
pl-PLPolish (Poland)Grupa krwi przeciwciała:granica wykrywalności:punkt w czasie:surowica lub osocze:uporządkowany:grupa krwi przeciwciała skrining.LISS
Synonyms: badanie przesiewowe w kierunku obecności przeciwciał grup krwi Przeciwciała grup krwi skrining przeciwciał grup krwi metodą z zastosowaniem roztworu soli o niskiej sile jonowej
zh-CNChinese (China)血型抗体:存在情况或阈值:时间点:血清/血浆:序数型:血型抗体筛查.LISS
Synonyms: 低离子强度氯化钠水溶液;低离子强度氯化钠水溶液法;低离子强度氯化钠溶液;低离子强度氯化钠溶液法;低离子强度盐水;低离子强度盐水（Low ionic strenght saline，LISS） 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 筛查 筛查方法;筛查法;筛查试验 筛查试验 筛选试验 血;全血 血型抗体（Ab） 血型抗体（Ab）筛查 血型抗体（Ab）筛查.LISS（低离子强度盐溶液、低离子强度盐水） 血库;血库检验;血库检验类;血库检验项目;血库检验项目类;血库类;血库试验;血库试验项目;血库试验项目类 血清或血浆 过筛 过筛试验

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75264-2