Version 2.78

Term Description

Antibody screening is used to demonstrate unexpected antibodies (other than ABO) and is performed on both donors and recipients to help ensure compatibility between recipient antibodies and donor red cells. Low ionic strength saline (LISS) is a blood banking potentiating agent that works by decreasing the repelling charges between red cells (zeta potential), thus packing the reds cells closer together for increased antibody bridging. This then decreases the incubation time for the sensitization phase in the antibody screening. A downside to using LISS is that it enhances the expression of cold antibodies and auto-antibodies that may not be significant. In addition, the ratio of serum to red cells must be adhered to strictly to maintain the ionic strength of the mixture. If ionic strength is too high, false negatives may occur, and if it is too low, false positives due to complement binding may occur.
Source: Regenstrief LOINC

Part Description

LP67167-4   Blood group antibody screen
Detects atypical IgG antibodies prior to transfusion or during pregnancy. The screening test is designed specifically to detect IgG antibodies and some IgM antibodies (non ABO) may also be detected. Antibodies detected by the antibody screen should then be identified, and a titer performed if the antibody identified is considered to be clinically significant during pregnancy. Source: LOINC partner 1

Fully-Specified Name

Component
Blood group antibody screen
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
LISS

Additional Names

Short Name
Bld gp Ab Scn SerPl Ql LISS
Display Name
Blood group antibody screen LISS Ql
Consumer Name Alpha Get Info
Blood group antibody screen, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
BLDBK
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
2564

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Examen de anticuerpos de grupos sanguineos:PrThr:Punto temporal:Suero o Plasma:Ord:Tampón salino de fuerza iónica baja
es-MX Spanish (Mexico) Examen de anticuerpos del grupo sanguíneo:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Solución salina de baja fuerza iónica (LISS)
et-EE Estonian (Estonia) Erütrotsütaarsete antikehade sõeluuring:PrThr:Pt:S/P:Ord:LISS
Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA French (Canada) Anticorps des groupes sanguins dépistage:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Salin hypotonique
fr-FR French (France) Anticorps irréguliers (RAI) dépistage:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:LISS
fr-BE French (Belgium) Anticorps des groupes sanguins dépistage:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:Salin hypotonique
Synonyms: Solution LISS
it-IT Italian (Italy) Gruppo sanguigno, screening anticorpo:PrThr:Pt:Siero/Plasma:Ord:LISS
Synonyms: Banca del sangue Plasma Presenza o Soglia Punto nel tempo (episodio) Screening anticorpo di gruppo sanguigno Siero Siero o Plasma Soluzione salina a bassa forza ionica (LISS)
nl-NL Dutch (Netherlands) bloedgroep antistofscreening:aanwezigheid:moment:serum of plasma:ordinaal:zoutoplossing met lage ionsterkte (LISS)
Synonyms: LISS
pl-PL Polish (Poland) Skryning przeciwciał grup krwi:granica wykrywalności:punkt w czasie:surowica lub osocze:półilościowy:standaryzowany roztwór soli o niskiej sile jonowej
pt-BR Portuguese (Brazil) Triagem de anticorpos grupo sanguíneo::Pt:Soro/Plas:Ord:LISS
ru-RU Russian (Russian Federation) Кровь группа антитело скрин:PrThr:ТчкВрм:Сыв/Плаз:Пор:Гипотонический раствор
Synonyms: Гипотонический водный раствор хлорида натрия (проба на кроссовместимость с потенциальным донором) Группа крови Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Kan grubu antikoru tarama:MevcEşik:Zmlı:Ser/Plaz:Srl:DİGS
Synonyms: Düşük iyonik güçteki salin Mevcut
zh-CN Chinese (China) 血型抗体筛查:存在情况或阈值:时间点:血清/血浆:序数型:低离子强度盐水法
Synonyms: 低离子强度氯化钠水溶液;低离子强度氯化钠水溶液法;低离子强度氯化钠溶液;低离子强度氯化钠溶液法;低离子强度盐水;低离子强度盐水(Low ionic strenght saline,LISS) 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 筛查 筛查试验 筛选试验 血;全血 血型抗体筛选 血库;血库检验;血库检验类;血库检验项目;血库检验项目类;血库类;血库试验;血库试验项目;血库试验项目类 血清或血浆 过筛 过筛试验

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75264-2