LOINC
Version 2.67

75264-2Blood group antibody screen [Presence] in Serum or Plasma by Low ionic strength saline (LISS)Active

Term Description

Antibody screening is used to demonstrate unexpected antibodies (other than ABO) and is performed on both donors and recipients to help ensure compatibility between recipient antibodies and donor red cells. Low ionic strength saline (LISS) is a blood banking potentiating agent that works by decreasing the repelling charges between red cells (zeta potential), thus packing the reds cells closer together for increased antibody bridging. This then decreases the incubation time for the sensitization phase in the antibody screening. A downside to using LISS is that it enhances the expression of cold antibodies and auto-antibodies that may not be significant. In addition, the ratio of serum to red cells must be adhered to strictly to maintain the ionic strength of the mixture. If ionic strength is too high, false negatives may occur, and if it is too low, false positives due to complement binding may occur.
Source: Regenstrief LOINC

Part Description

LP67167-4   Blood group antibody screen
Detects atypical IgG antibodies prior to transfusion or during pregnancy. The screening test is designed specifically to detect IgG antibodies and some IgM antibodies (non ABO) may also be detected. Antibodies detected by the antibody screen should then be identified, and a titer performed if the antibody identified is considered to be clinically significant during pregnancy. Source: LOINC partner 1

Fully-Specified Name

Component
Blood group antibody screen
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
LISS

Additional Names

Short Name
Bld gp Ab Scn SerPl Ql LISS
Display Name
Blood group antibody screen LISS Ql

Basic Attributes

Class
BLDBK
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
血型抗体筛查:存在情况或阈值:时间点:血清/血浆:序数型:低离子强度盐水法
nl-NLDutch (NETHERLANDS)
bloedgroep antistofscreening:aanwezigheid:moment:serum of plasma:ordinaal:zoutoplossing met lage ionsterkte (LISS)
et-EEEstonian (ESTONIA)
Erütrotsütaarsete antikehade sõeluuring:PrThr:Pt:S/P:Ord:LISS
fr-BEFrench (BELGIUM)
Anticorps des groupes sanguins dépistage:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:Salin hypotonique
fr-CAFrench (CANADA)
Anticorps des groupes sanguins dépistage:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Salin hypotonique
fr-FRFrench (FRANCE)
Anticorps irréguliers (RAI) dépistage:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:LISS
it-ITItalian (ITALY)
Gruppo sanguigno, screening anticorpo:PrThr:Pt:Siero/Plasma:Ord:LISS
pt-BRPortuguese (BRAZIL)
ru-RURussian (RUSSIAN FEDERATION)
Кровь группа антитело скрин:PrThr:ТчкВрм:Сыв/Плаз:Пор:Гипотонический раствор
es-ESSpanish (SPAIN)
Examen de anticuerpos de grupos sanguineos:PrThr:Punto temporal:Suero o Plasma:Ord:Tampón salino de fuerza iónica baja
tr-TRTurkish (TURKEY)
Kan grubu antikoru tarama:MevcEşik:Zmlı:Ser/Plaz:Srl:DİGS

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75264-2