75411-9

Ebola Zaire virus RNA [Presence] in Plasma or Blood by NAA with probe detection

Active

Term Description

The Ebola Zaire PCR assay presumptively detects Ebola Zaire virus, a single-stranded RNA virus identified in the 2014 West Africa outbreak. The assay is used for testing individuals with signs and symptoms of Ebola virus infection, those who are at risk for or may have been exposed to the Ebola Zaire virus, or in accordance with current public health recommendations. The definitive identification of the Ebola Zaire virus requires additional testing and confirmation procedures in consultation with public health. This term was developed for, but is not limited to, use with the Ebola Zaire Target 1 (EZ1) real-time reverse transcription (rRT) polymerase chain reaction (TaqMan®) assay (EZ1 assay), which is run on plasma or whole blood specimens. As of August 2014, the EZ1 assay is approved for use under an FDA Emergency Use Authorization (EUA) http://www.fda.gov/downloads/MedicalDevices/Safety/EmergencySituations/UCM408334.pdf by specified laboratories and clinical laboratory personnel who have been trained on instruments authorized by the U.S. Department of Defense.

Part Description

LP185762-4 Ebola Zaire virus
Ebola virus is one cause of viral hemorrhagic fever disease and has 5 subspecies, including Ebola Zaire, which was the type identified in the West Africa outbreak in 2014. Ebola is transmitted through direct contact with the blood or bodily fluids of an infected symptomatic person or though exposure to objects (such as needles) that have been contaminated with infected secretions. Symptoms most often appear 8 to 10 days after exposure to the virus and include fever, headache, joint and muscle aches, weakness, diarrhea, vomiting, stomach pain, lack of appetite, and abnormal bleeding.
Ebola Zaire is a single-stranded RNA virus, and it is the viral RNA that is detected by the Ebola Zaire real-time reverse transcription (rRT) polymerase chain reaction assay. Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Package Insert	U.S. Food and Drug Administration	Ebola Zaire (EZ1) rRT-PCR (Taq-Man®) assayInstrument: Applied Biosystems® 7500 Fast Dx Real-Time PCR Instrument (ABI 7500 Fast Dx), Roche LightCycler® (LightCycler), and Biofire Defense Joint Biological Agent Identification and Diagnostic System (JBAIDS) Ebola Zaire (EZ1)

LOINC Names Get Info

Fully-Specified Name: Ebola Zaire virus RNA:PrThr:Pt:Plas/Bld:Ord:Probe.amp.tar
Long Common Name: Ebola Zaire virus RNA [Presence] in Plasma or Blood by NAA with probe detection
Short Name: EZ1 RNA PlasBld Ql NAA+probe
Display Name: Ebola Zaire virus RNA NAA+probe Ql (P/Bld)
Consumer Name Alpha Get Info: Ebola Zaire virus, Blood

Part Model Get Info

Component
Ebola Zaire virus RNA
LP185761-6
- Analyte
  Ebola Zaire virus RNA
  LP185761-6
  - Component Numerator
    Ebola Zaire virus RNA
    LP185761-6
    - Component Numerator Core
      Ebola Zaire virus
      LP185762-4
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Plas/Bld
LP185760-8
- System Core
  Plas/Bld
  LP185760-8
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL2999-2

Source: Regenstrief LOINC

Answer	Code	Score	Answer ID
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Uncertain			LA12719-3
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.50
Last Updated: Version 2.63 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus Ebola-Zaire RNA:Přítomnost nebo práh:Časový bod:Plazma/krev:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	Ebola-Zaire-Virus RNA:Nachweis oder Schwellenwert:Zeitpunkt:Plasma oder Blut:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Ιός Έμπολα του Ζαΐρ RNA:PrThr:Pt:Πλάσμα/Αίμα:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: MICRO Ord PrThr Pt RNA Αίμα Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός Έμπολα του Ζαΐρ Πλάσμα Πλάσμα/Αίμα
es-ES	Spanish (Spain)	Virus Ebola Zaire RNA:PrThr:Punto temporal:Plasma/Sangre:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ARN del virus del Ébola Zaire:Presencia o umbral:Punto temporal:Plasma o sangre:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Ebola Zaïre virus ARN:Présence/Seuil:Ponctuel:Plasma/Sang:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Zaire ebolavirus RNA:PrThr:Pt:Plasma/Sangue:Ord:Sonda.amp.tar Synonyms: Microbiologia Plasma Plasma o Sangue Presenza o Soglia Punto nel tempo (episodio) Sangue Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Ebola Zaïre virus RNA:aanwezigheid:moment:plasma of bloed:ordinaal:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	Wirus Ebola Zaire RNA:granica wykrywalności:punkt w czasie:osocze/krew:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy osocze lub krew RNA wirusa Ebola Zaire Wirus Ebola Zaire
tr-TR	Turkish (Turkey)	Ebola Zaire virüs RNA:MevcEşik:Zmlı:Plaz/Kan:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	扎伊尔埃博拉病毒 RNA:存在情况或阈值:时间点:血浆/全血:序数型:探针法.基因扩增.靶向 Synonyms: Zaire ebolavirus;zaire strain of ebola virus;埃博拉病毒扎伊尔株;扎伊尔伊波拉病毒传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针血;血液血浆或全血;血浆/血液;血浆或血液

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.