75547-0
Noninvasive prenatal fetal aneuploidy and microdeletion panel based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific circulating cell free (ccf) DNA
Active
Term Description
Noninvasive prenatal screening is used to assess fetal risk for various genetic conditions without requiring invasive maternal procedures such as amniocentesis or chorionic villus sampling. Cell-free DNA (cfDNA) in maternal plasma comes from both fetal and maternal sources, and depending on the technology used, this DNA can be used to determine fetal risk for a variety of conditions including aneuploidy (e.g., Trisomy 21, Monosomy X) and microdeletions (e.g., 22q11.2 deletion). This panel was developed for, but is not limited in use to, Natera's Panorama prenatal test, which incorporates SNP analysis of maternal white blood cell DNA with combined maternal and fetal cfDNA SNP analysis. Natera's proprietary informatics analysis method (NATUS) effectively subtracts the maternal genotype from the cfDNA genotype and analyzes the remaining fetal cfDNA genotype for certain aneuploidies and microdeletion syndromes.
Panel Hierarchy
Details for each LOINC in Panel LHC-Forms
| LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
|---|---|---|---|---|
| 75547-0 | Noninvasive prenatal fetal aneuploidy and microdeletion panel based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific circulating cell free (ccf) DNA | |||
| Indent43993-5 | Age at delivery | R | a | |
| Indent18185-9 | Gestational age | R | wk | |
| Indent75607-2 | Paternal sample received Qualitative | R | ||
| Indent75605-6 | Cell-free DNA.fetal/Cell-free DNA.total in Plasma cell-free DNA by Dosage of chromosome-specific cfDNA | R | % | |
| Indent75606-4 | Cell-free DNA.fetal/Cell-free DNA.total in Plasma cell-free DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75604-9 | Fetal sex in Cell-free+Maternal WBC DNA by Dosage of chromosome specific circulating cell free (ccf) DNA | C | ||
| Indent75560-3 | Fetal Trisomy 21 prior risk [Likelihood] Based on maternal age | R | {risk} | |
| Indent75562-9 | Fetal Trisomy 21 prior risk [Likelihood] Based on maternal age Narrative | O | ||
| Indent75561-1 | Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | R | {risk} | |
| Indent75563-7 | Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75564-5 | Fetal Trisomy 21 risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | R | ||
| Indent75565-2 | Comment on fetal Trisomy 21 risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75554-6 | Fetal Trisomy 18 prior risk [Likelihood] Based on maternal age | R | {risk} | |
| Indent75556-1 | Fetal Trisomy 18 prior risk [Likelihood] Based on maternal age Narrative | O | ||
| Indent75555-3 | Fetal Trisomy 18 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | R | {risk} | |
| Indent75557-9 | Fetal Trisomy 18 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75558-7 | Fetal Trisomy 18 risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | R | ||
| Indent75559-5 | Comment on fetal Trisomy 18 risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75546-2 | Fetal Trisomy 13 prior risk [Likelihood] Based on maternal age | R | {risk} | |
| Indent75550-4 | Fetal Trisomy 13 prior risk [Likelihood] Based on maternal age Narrative | O | ||
| Indent75548-8 | Fetal Trisomy 13 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | R | {risk} | |
| Indent75551-2 | Fetal Trisomy 13 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75552-0 | Fetal Trisomy 13 risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | R | ||
| Indent75553-8 | Comment on fetal Trisomy 13 risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75566-0 | Fetal Monosomy X prior risk [Likelihood] Based on maternal age | R | {risk} | |
| Indent75568-6 | Fetal Monosomy X prior risk [Likelihood] Based on maternal age Narrative | O | ||
| Indent75567-8 | Fetal Monosomy X risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | R | {risk} | |
| Indent75569-4 | Fetal Monosomy X risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75570-2 | Fetal Monosomy X risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | R | ||
| Indent75571-0 | Comment on fetal Monosomy X risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75572-8 | Fetal Triploidy risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | R | ||
| Indent75573-6 | Comment on fetal Triploidy risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75574-4 | Fetal 22q11.2 deletion prior risk [Likelihood] based on general population risk | C | {risk} | |
| Indent75575-1 | Fetal 22q11.2 deletion prior risk [Likelihood] based on general population risk Narrative | O | ||
| Indent75576-9 | Fetal 22q11.2 deletion risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | C | {risk} | |
| Indent75577-7 | Fetal 22q11.2 deletion risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75578-5 | Fetal 22q11.2 deletion risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | C | ||
| Indent75579-3 | Comment on fetal 22q11.2 deletion risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75598-3 | Fetal 1p36 deletion prior risk [Likelihood] based on general population risk | C | {risk} | |
| Indent75599-1 | Fetal 1p36 deletion prior risk [Likelihood] based on general population risk Narrative | O | ||
| Indent75600-7 | Fetal 1p36 deletion risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | C | {risk} | |
| Indent75601-5 | Fetal 1p36 deletion risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75602-3 | Fetal 1p36 deletion risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | C | ||
| Indent75603-1 | Comment on fetal 1p36 deletion risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75586-8 | Fetal Angelman syndrome prior risk [Likelihood] based on general population risk | C | {risk} | |
| Indent75587-6 | Fetal Angelman syndrome prior risk [Likelihood] based on general population risk Narrative | O | ||
| Indent75588-4 | Fetal Angelman syndrome risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | C | {risk} | |
| Indent75589-2 | Fetal Angelman syndrome risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75590-0 | Fetal Angelman syndrome risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | C | ||
| Indent75591-8 | Comment on fetal Angelman syndrome risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75592-6 | Fetal 5p deletion prior risk [Likelihood] based on general population risk | C | {risk} | |
| Indent75593-4 | Fetal 5p deletion prior risk [Likelihood] based on general population risk Narrative | O | ||
| Indent75594-2 | Fetal 5p deletion risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | C | {risk} | |
| Indent75595-9 | Fetal 5p deletion risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75596-7 | Fetal 5p deletion risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | C | ||
| Indent75597-5 | Comment on fetal 5p deletion risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75580-1 | Fetal Prader-Willi syndrome prior risk [Likelihood] based on general population risk | C | {risk} | |
| Indent75581-9 | Fetal Prader-Willi syndrome prior risk [Likelihood] based on general population risk Narrative | O | ||
| Indent75582-7 | Fetal Prader-Willi syndrome risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA | C | {risk} | |
| Indent75583-5 | Fetal Prader-Willi syndrome risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | O | ||
| Indent75584-3 | Fetal Prader-Willi syndrome risk [Interpretation] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Qualitative | C | ||
| Indent75585-0 | Comment on fetal Prader-Willi syndrome risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative | C | ||
| Indent75544-7 | Noninvasive prenatal testing overall interpretation Qualitative | R | ||
| Indent75545-4 | Noninvasive prenatal testing comment [Text] | C | ||
| Indent75608-0 | Citation [Bibliographic Citation] in Referral lab test Narrative | O | ||
| Indent68989-3 | Performing laboratory [Address] | R | ||
| Indent75549-6 | Performing laboratory phone number | R |
LOINC Names Get Info
- Fully-Specified Name
- Noninvasive prenatal fetal aneuploidy and microdeletion panel:
-: Pt: WBC.DNA+Plas.cfDNA: -: Dosage of chromosome specific cf DNA - Long Common Name
- Noninvasive prenatal fetal aneuploidy and microdeletion panel based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific circulating cell free (ccf) DNA
- Short Name
- NIP aneu microdel pnl WBC.DNA+cfDNA
- Display Name
- Noninvasive prenatal fetal aneuploidy and microdel panel Dosage of chromosome-specific cfDNA (Plasma cell-free+WBC DNA)
- Consumer Name Alpha Get Info
- Fetal Noninvasive prenatal fetal aneuploidy and Microdel panel
Part Model Get Info
- Component
- Noninvasive prenatal fetal aneuploidy and microdeletion panel
LP185919-0
- Analyte
- Noninvasive prenatal fetal aneuploidy and microdeletion panel
LP185919-0
- Component Numerator
- Noninvasive prenatal fetal aneuploidy and microdeletion panel
LP185919-0
- Component Numerator Core
- Noninvasive prenatal fetal aneuploidy and microdeletion panel
LP185919-0
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- -
LP6769-6
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- WBC.DNA+Plas.cfDNA
LP185797-0
- System Core
- WBC.DNA+Plas.cfDNA
LP185797-0
- Super System
- NULL
- Scale
- -
LP7747-1
- Method
- Dosage of chromosome specific cf DNA
LP172871-8
Basic Attributes
- Class
- PANEL.MOLPATH
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Order
- Panel Type
- Panel
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| ar-JO | Arabic (Jordan) | فحص ما قبل الولادة غير الجراحي للكشف عن اختلالات الصيغة الصبغية الجنينية والحذف الصغير، بالإعتماد على الحمض النووي الخالي من الخلايا وكريات الدم البيضاء في البلازما، بقياس جرعة الحمض النووي الخالي من الخلايا المنتشر في الدورة الدموية والمحدد للكروموسومات |
| cs-CZ | Czech (Czechia) | Fetální aneuploidie a mikrodelece neinvazivní prenatální panel: |
| el-GR | Greek (Greece) | Πίνακας μη επεμβατικής προγεννητικής εμβρυϊκής ανευπλοειδίας και μικροδιαγραφής: Synonyms: - MOLPATH PANEL.MOLPATH Pt Αριθμός λευκών αιμοσφαιρίων Αριθμός λευκών αιμοσφαιρίων.DNA+Πλάσμα.cfDNA Δοσολογία ειδικού χρωμοσωμικού cf DNA Πίνακας μη επεμβατικής προγεννητικής εμβρυϊκής ανευπλοειδίας και μικροδιαγραφής Πλάσμα Πλάσμα.cfDNA |
| es-ES | Spanish (Spain) | Panel prenatal no invasivo de aneuploidía y microdeleción fetal: |
| es-MX | Spanish (Mexico) | Panel de microdeleción y aneuploidía fetal prenatal no invasiva: |
| fr-FR | French (France) | Aneuploïdie et microdélétion foetale prénatale non invasive panel: |
| it-IT | Italian (Italy) | Microdelezione e aneuploidia fetale prenatale non invasiva, panel: Synonyms: DNA libero circolante nel plasma Dosaggio di DNA libero fetale circolante cromosoma Globuli bianchi Globuli bianchi+DNA libero circolante nel plasma Panel microdelezione e aneuploidia fetale prenatale non invasiva Patologia molecolare Plasma Punto nel tempo (episodio) Set di prescrizione patologia molecolare |
| zh-CN | Chinese (China) | 无创性产前胎儿非整倍体性与染色体微缺失组套: Synonyms: WBC.DNA+血浆.cfDNA; |
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LOINC Copyright
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