75736-9
Lysophosphatidylcholine(16:0) [Moles/volume] in Plasma
Active
Term Description
A screening aid in patients presenting with decreased high density lipid (HDL) cholesterol, to investigate potential hypoalphalipoproteinemia phenotypes prior to confirmatory molecular testing.
Part Description
LP185934-9 Lysophosphatidylcholine(16:0)
Lysophosphatidylcholine(16:0), or LysoPC(16:0), is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. Lysophosphatidylcholines can have different combinations of fatty acids of varying lengths and saturation attached at the C-1 (sn-1) position. Fatty acids containing 16, 18 and 20 carbons are the most common. LysoPC(16:0), in particular, consists of one chain of palmitic acid at the C-1 position. The palmitic acid moiety is derived from fish oils, milk fats, vegetable oils and animal fats. Lysophosphatidylcholine is found in small amounts in most tissues. It is formed by hydrolysis of phosphatidylcholine by the enzyme phospholipase A2, as part of the de-acylation/re-acylation cycle that controls its overall molecular species composition. It can also be formed inadvertently during extraction of lipids from tissues if the phospholipase is activated by careless handling. In blood plasma significant amounts of lysophosphatidylcholine are formed by a specific enzyme system, lecithin:cholesterol acyltransferase (LCAT), which is secreted from the liver. The enzyme catalyzes the transfer of the fatty acids of position sn-2 of phosphatidylcholine to the free cholesterol in plasma, with formation of cholesterol esters and lysophosphatidylcholine. Lysophospholipids have a role in lipid signaling by acting on lysophospholipid receptors (LPL-R). LPL-R's are members of the G protein-coupled receptor family of integral membrane proteins.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
LysoPC(16:0)
LOINC Names Get Info
- Fully-Specified Name
- Lysophosphatidylcholine(16:0):
SCnc: Pt: Plas: Qn: - Long Common Name
- Lysophosphatidylcholine(16:0) [Moles/volume] in Plasma
- Short Name
- LysoPC(16:0) Plas-sCnc
- Display Name
- LysoPC(16:0) (P) [Moles/Vol]
- Consumer Name Alpha Get Info
- LysoPC(16:0), Blood
Part Model Get Info
- Component
- Lysophosphatidylcholine(16:0)
LP185934-9
- Analyte
- Lysophosphatidylcholine(16:0)
LP185934-9
- Component Numerator
- Lysophosphatidylcholine(16:0)
LP185934-9
- Component Numerator Core
- Lysophosphatidylcholine(16:0)
LP185934-9
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- SCnc
LP6860-3
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Plas
LP7479-1
- System Core
- Plas
LP7479-1
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.50 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Lysofosfatidylcholin (16: |
| el-GR | Greek (Greece) | Λυσοφωσφατιδυλοχολίνη (16: Synonyms: CHEM Pt Qn SCnc Λυσοφωσφατιδυλοχολίνη (16: |
| es-ES | Spanish (Spain) | Lisofosfatidilcolina (16: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Lisofosfatidilcolina (16: |
| fr-FR | French (France) | Lysophosphatidylcholine(16: |
| it-IT | Italian (Italy) | Lisofosfatidilcolina(16: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | lysofosfatidylcholine(16: |
| tr-TR | Turkish (Turkey) | Lizofosfatidilkolin(16: |
| zh-CN | Chinese (China) | 溶血磷脂酰胆碱(16: Synonyms: 克分子浓度; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://