76023-1
N-acetyl-L-aspartate/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP18445-4 N-acetyl-L-aspartate
N-Acetylaspartic acid, or N-acetylaspartate (NAA), is a derivative of aspartic acid with a formula of C6H9NO5 and a molecular weight of 175.139.
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Source: Wikipedia, N-acetyl-L-aspartate
LP18445-4 N-acetyl-L-aspartate
N-acetyl-L-aspartate (NAA) normally occurs in high concentrations in the brain tissue, and its function is not well-understood. An elevation of NAA in urine and plasma is a marker of Canavan disease, a rare genetic disorder characterized by hypotonia, severe cognitive delay, blindness, demyelination and leukodystrophy, and typically death by 18 months of life. Canavan disease is caused by a mutation in the ASPA gene, which encodes aspartoacylase, the enzyme that metabolizes NAA. [OMIM: 271900]
Source: Regenstrief LOINC, OMIM: 271900
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- N-acetyl-L-aspartate/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- N-Ac-L-Asp/Creat Ur-sRto
- Display Name
- N-acetyl-L-aspartate/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- N-acetyl-L-aspartate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 11785
Member of these Panels
LOINC | Long Common Name |
---|---|
48797-5 | Organic acids panel - Urine |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: N-Acetyl-Aspartat/Kreatinin-Ratio /U |
es-ES | Spanish (Spain) | N-acetil-L-aspartato/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | N-acetil-L-aspartato / Creatinina: |
fr-CA | French (Canada) | N-acétyl-l-aspartate/Créatinine: |
fr-FR | French (France) | N-acétyl-L-aspartate/créatinine: |
fr-BE | French (Belgium) | N-acétyl-l-aspartate/Créatinine: |
it-IT | Italian (Italy) | N-acetil-L-aspartato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
nl-NL | Dutch (Netherlands) | N-acetyl-L-aspartaat/creatinine: Synonyms: kreatinine |
ru-RU | Russian (Russian Federation) | N-ацетил-L-аспартат/Креатинин: Synonyms: Количественный Мольная доля; |
tr-TR | Turkish (Turkey) | N-asetil-L-aspartat/Kreatinin: Synonyms: SubsOranı |
zh-CN | Chinese (China) | N-乙酰-L-天门冬氨酸/肌酐: Synonyms: Asp; |
Example Units
Unit | Source |
---|---|
mmol/mmol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=76023-1
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright