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Term Description

Mannose-6-phosphate isomerase (MPI) levels are measured in fibroblasts for the diagnosis of congenital disorders of glycosylation (CDG), including CDG types Ia and Ib (phosphomannose isomerase deficiency, or MPI-CDG).

Part Description

LP186037-0   Mannose-6-phosphate isomerase
Mannose-6-phosphate isomerase, also known as phosphomannose isomerase, catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate. It is encoded by the MPI gene, which is located on chromosome 15q24.1. Mannose-6-phosphate isomerase deficiency is the cause of congenital disorder of glycosylation type Ib (CDG Ib), an autosomal recessive disorder characterized by chronic diarrhea with failure to thrive, protein-losing enteropathy, and coagulopathy. CDG Ib is different from the other CDGs in that it does not have significant central nervous system involvement. [OMIM: 602579] Source: Regenstrief LOINC, OMIM: 602579

LOINC Names Get Info

Fully-Specified Name
Mannose-6-phosphate isomerase:CCnt:Pt:Fibroblasts:Qn:
Long Common Name
Mannose-6-phosphate isomerase [Enzymatic activity/mass] in Fibroblast
Short Name
M6PI Fib-cCnt
Display Name
Mannose-6-phosphate isomerase (Fibroblast) [Catalytic activity/Mass]
Consumer Name Alpha Get Info
Mannose-6-phosphate isomerase, Fibroblast

Part Model Get Info

  • Component
    Mannose-6-phosphate isomerase
    LP186037-0
    • Analyte
      Mannose-6-phosphate isomerase
      LP186037-0
      • Component Numerator
        Mannose-6-phosphate isomerase
        LP186037-0
        • Component Numerator Core
          Mannose-6-phosphate isomerase
          LP186037-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CCnt
    LP6790-2
  • Time
    Pt
    LP6960-1
  • System
    Fibroblasts
    LP7234-0
    • System Core
      Fibroblasts
      LP7234-0
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.50
Last Updated
Version 2.54 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Manóza-6-fosfátizomeráza:Katalytický obsah:Časový bod:Fibroblast:Kvantitativní:
el-GRGreek (Greece)Ισομεράση 6-φωσφορικής μαννόζης:CCnt:Pt:Ινοβλάστες:Qn:
Synonyms: CCnt CHEM Pt Qn Ινοβλάστες Ισομεράση 6-φωσφορικής μαννόζης Μαννόζη Φωσφορικό
es-ESSpanish (Spain)Manosa-6-fosfato isomerasa:Contenido catalítico:Punto temporal:Fibroblastos:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Isomerasa manosa-6-fosfato:Contenido catalítico:Punto temporal:Fibroblasto:Cuantitativo:
fr-FRFrench (France)Mannose-6-phosphate isomérase:Catalytique/Masse:Ponctuel:Fibroblastes:Numérique:
it-ITItalian (Italy)Mannosio-6-fosfato isomerasi:CCnt:Pt:Fibroblasti:Qn:
Synonyms: Chimica Contenuto Catalitico Fibroblasto Punto nel tempo (episodio)
nl-NLDutch (Netherlands)mannose-6-fosfaatisomerase:enzymatische activiteit/massa:moment:fibroblast:kwantitatief:
tr-TRTurkish (Turkey)Mannoz-6-fosfat izomeraz:Ktlİçrk:Zmlı:Fibroblastlar:Kant:
zh-CNChinese (China)甘露糖-6-磷酸异构酶:催化含量:时间点:成纤维细胞:定量型:
Synonyms: i Phos;Phos;Pi;PO4;总磷酸;无机磷酸;无机磷酸;磷酸根;磷酸盐;磷酸酯 催化含量(单位质量);单位质量的酶单位数 别构酶 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 磷酸甘露糖异构酶;MPI;M6PI;M-6-PI 纤维原细胞;纤维母细胞

Example Units

UnitSource
nmol/min/mg{protein}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76027-2