Version 2.78

Term Description

Microorganism identification by MALDI-TOF (matrix-assisted laser desorption ionization time of flight) is a diagnostic test for identifying the specific microorganism(s), i.e., bacteria and/or fungi, responsible for an infection. MALDI-TOF is a form of mass spectrometry that analyzes the proteins contained in an isolated colony. The resulting mass spectrum is compared to a reference database of bacterial and fungal protein mass spectra in order to identify the organism(s) present in the test sample. This term was created for, but is not limited in use to, bioMerieux's VITEK MS system, which is indicated for use to aid in the diagnosis of bacterial and fungal infections.
Source: Regenstrief LOINC

Part Descriptions

LP14559-6   Microorganism
A microorganism or microbe is an organism that is microscopic (too small to be visible to the naked eye). Microorganisms are often described as single-celled, or unicellular organisms; however, some unicellular protists are visible to the naked eye, and some multicellular species are microscopic. The study of microorganisms is called microbiology. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Microorganism (Wikipedia)

LP186074-3   MS.MALDI-TOF
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is a type of mass spectrometry (MS). MALDI-TOF MS consists of three primary steps: 1) mixing the sample with an organic matrix, which provides a scaffolding and also protons for the ionization process; 2) applying a laser to the matrix, which absorbs energy from the laser and releases it into the sample, which causes the sample to desorb and form singly charged ions; and 3) using a flight tube to analyze the mass of the ions, ultimately resulting in a mass spectrum in which the mass-to-charge is plotted against signal intensity. MALDI-TOF is a soft ionization technique, meaning that molecules remain relatively intact during ionization. Because of this property, MALDI-TOF can be used for protein analysis; in contrast, older MS techniques cause extensive protein fragmentation and therefore cannot be used for this purpose. One application of MALDI-TOF is in clinical microbiology; compared to traditional methods, MALDI-TOF is faster and more accurate in identifying specific microorganisms. PMID: 23824373 Source: Regenstrief LOINC, PMID: 23824373

Fully-Specified Name

Component
Microorganism
Property
Prid
Time
Pt
System
Isolate
Scale
Nom
Method
MS.MALDI-TOF

Additional Names

Long Common Name
Microorganism identified in Isolate by MS.MALDI-TOF
Short Name
Microorganism Islt MS.MALDI-TOF
Display Name
Microorganism identified MS.MALDI-TOF Nom (Isol)
Consumer Name Alpha Get Info
Microorganism test

Example Answer List: LL3210-3

Source: bioMerieux
Externally Defined
Yes
Link to External List
http://www.vitekms.com/knowledgebase.html

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.78
Change Reason
Release 2.78: COMPONENT: Removed "Identified" from the component because it is implied by the Property "Prid";
Order vs. Observation
Both
Common Test Rank Get Info
8975

Member of these Panels

LOINC Long Common Name
92254-2 Microorganism identification and resistance pattern determination panel by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Microorganismo:Presencia o identidad:Punto temporal:Aislado:Nom:MS.MALDI-TOF
es-MX Spanish (Mexico) Microorganismo identificado:Presencia o identidad:Punto temporal:Aislado:Nominal:SRA. MALDI-TOF
fr-FR French (France) Microorganisme identifié:Identification:Ponctuel:Isolat:Résultat nominal:Spectrométrie MALDI-TOF
it-IT Italian (Italy) Microrganismo:Prid:Pt:Isolato:Nom:MS.MALDI-TOF
Synonyms: Microbiologia Presenza o Identità Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) micro-organisme:identificator:moment:isolaat:nominaal:MALDI-TOF
Synonyms: massaspectometrie; Malditof
pl-PL Polish (Poland) Mikroorganizm:wykrycie lub identyfikacja:punkt w czasie:izolat:cecha:spektrometria mas.MALDI-TOF
Synonyms: Mikroorganizm
zh-CN Chinese (China) 微生物:存在与否或特征标识:时间点:分离株:名义型:MS.MALDI-TOF
Synonyms: 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 基质辅助激光解吸/电离飞行时间质谱;基质辅助激光解吸电离飞行时间质谱;基质辅助激光解吸飞行时间质谱;基质辅助激光解析电离飞行时间质谱;Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry;MALDI-TOF-MS;Matrix-assisted laser desorption ionization-time of flight 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76346-6