LP186074-3
MS.MALDI-TOF
Active
Description
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is a type of mass spectrometry (MS). MALDI-TOF MS consists of three primary steps: 1) mixing the sample with an organic matrix, which provides a scaffolding and also protons for the ionization process; 2) applying a laser to the matrix, which absorbs energy from the laser and releases it into the sample, which causes the sample to desorb and form singly charged ions; and 3) using a flight tube to analyze the mass of the ions, ultimately resulting in a mass spectrum in which the mass-to-charge is plotted against signal intensity. MALDI-TOF is a soft ionization technique, meaning that molecules remain relatively intact during ionization. Because of this property, MALDI-TOF can be used for protein analysis; in contrast, older MS techniques cause extensive protein fragmentation and therefore cannot be used for this purpose. One application of MALDI-TOF is in clinical microbiology; compared to traditional methods, MALDI-TOF is faster and more accurate in identifying specific microorganisms. PMID: 23824373 Source: Regenstrief LOINC, PMID: 23824373
Basic Part Properties
- Part Name
- MS.MALDI-TOF
- Part Display Name
- MS.MALDI-TOF
- Part Type
- Method (Describes the method by which the test was performed)
- Created On
- 2014-10-17
- Construct for LOINC Short Name
- MS.MALDI-TOF
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| nl-NL | Dutch (Netherlands) | MALDI-TOF Synonyms: massaspectometrie; |
| zh-CN | Chinese (China) | MS.MALDI-TOF Synonyms: 基质辅助激光解吸/电离飞行时间质谱; |
| es-ES | Spanish (Spain) | MS.MALDI-TOF |
| it-IT | Italian (Italy) | MS.MALDI-TOF |
| fr-FR | French (France) | Spectrométrie MALDI-TOF |
| pl-PL | Polish (Poland) | spektrometria mas.MALDI-TOF |
| el-GR | Greek (Greece) | MS.MALDI-TOF Synonyms: MS.MALDI-TOF |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://