Version 2.79

Term Description

This term was created for but not limited in use to, the cobas Tacrolimus test kit which uses a competition principle immunoassay.

Part Descriptions

LP15182-6   Tacrolimus
Tacrolimus (also known as FK-506 or Prograf) is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis. It has strong immunosuppressive properties and is commonly used to prevent allograft rejection in transplant recipients. One of its modes of action is to prevent T-lymphocyte activation. Source: National Library of Medicine, MeSH 2006

LP15182-6   Tacrolimus
Tacrolimus (also called FK-506 or fujimycin, Prograf, Advagraf, or Protopic) is amacrolide lactone, calcineurin inhibitor immunosuppresent used mainly after allogeneic organ transplant to lower the risk of organ rejection. It possesses strong immunosuppressive activity by preventing the activation by of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2-mediated diseases such as Kimura's disease, and the skin condition vitiligo. There are potentially severe side effects from doses that are either too low or too high; inadequate tacrolimus concentrations may result in rejection of the transplanted organ, while high levels may lead to severe adverse effects includin nephrotoxicity, neurotoxicity, gastrointestinal disturbances, diabetogenesis, hypertension and malignant complications. [Wikipedia: Tacrolimus] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Tacrolimus

Fully-Specified Name

Component
Tacrolimus
Property
SCnc
Time
Pt
System
Bld
Scale
Qn
Method
IA

Additional Names

Long Common Name
Tacrolimus [Moles/volume] in Blood by Immunoassay
Short Name
Tacrolimus Bld IA-sCnc
Display Name
Tacrolimus IA (Bld) [Moles/Vol]
Consumer Name Alpha Get Info
Tacrolimus, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.56 (MIN)
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG47896-2 Tacrolimus|Pt|Bld|IA

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Tacrolimus:Stoffmengenkonzentration:Zeitpunkt:Blut:Quantitativ:Immunoassay
el-GR Greek (Greece) Τακρόλιμους:SCnc:Pt:Αίμα:Qn:IA
Synonyms: SCnc Τακρόλιμους
es-MX Spanish (Mexico) Tacrolimus:Concentración de sustancias:Punto temporal:Sangre:Cuantitativo:Inmunoensayo
es-ES Spanish (Spain) Tacrolimus:Concentración de sustancia:Punto temporal:Sangre:Qn:IA
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Takroliimus:SCnc:Pt:B:Qn:IA
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Veri
fr-CA French (Canada) Tacrolimus:Concentration de substance:Temps ponctuel:Sang:Quantitatif:IA
fr-FR French (France) Tacrolimus:Moles/Volume:Ponctuel:Sang:Numérique:Immunoanalyse
fr-BE French (Belgium) Tacrolimus:Concentration de substance:Temps ponctuel:Sang:Quantitatif:IA
it-IT Italian (Italy) Tacrolimus:SCnc:Pt:Sangue:Qn:IA
Synonyms: Concentrazione di Sostanza FK-506 Immunoassay Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) tacrolimus:mol/volume:moment:bloed:kwantitatief:immunoassay
Synonyms: IA
ru-RU Russian (Russian Federation) Такролимус:МолКонц:ТчкВрм:Кр:Колич:IA
Synonyms: Количественный Кровь Молярность;Молярная объёмная концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Takrolimus:SubKons:Zmlı:Kan:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 他克莫司:物质的量浓度:时间点:全血:定量型:免疫测定法
Synonyms: 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 普乐可复 毒品 毒品类 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76494-4