LOINC
Version 2.68

76546-1Breast cancer 10-year risk of distant recurrence panel by ProsignaActive

Term Description

A 10-year breast cancer distant recurrence risk panel created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone. The panel includes terms for primary tumor size, lymph node status, distant recurrence risk score, and distance recurrence risk classification. The 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes: 1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years.
Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
76546-1 Breast cancer 10-year risk of distant recurrence panel by Prosigna
Indent76397-9 Lymph node involvement
Indent21889-1 Size Tumor mm
Indent76544-6 Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna {score}
Indent76545-3 Breast cancer 10-year risk of distant recurrence classification [Interpretation] Qualitative by Prosigna

Fully-Specified Name

Component
Breast cancer 10Y risk of distant recurrence panel
Property
-
Time
Pt
System
^Patient
Scale
-
Method
Prosigna

Additional Names

Short Name
Brst ca 10Y risk dist recur Pnl Prosigna
Display Name
Breast cancer 10-year risk of distant recurrence panel Prosigna

Basic Attributes

Class
PANEL.MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.52
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

zh-CNChinese (CHINA)
乳腺癌远处转移 10 年风险组套:-:时间点:^患者:-:Prosigna
fr-FRFrench (FRANCE)
Risque de récidive du cancer du sein à 10 ans panel:-:Ponctuel:Patient:-:Test Prosigna
it-ITItalian (ITALY)
Tumore della mammella, rischio 10 anni di recidive tumorali, panel:-:Pt:^Paziente:-:Prosigna
es-ESSpanish (SPAIN)
Panel genético para el riesgo a 10 años de recurrencia en el cancer de mama:Propiedades mixtas (sólo paneles):Punto temporal:^paciente:-:Sustrato 2,3-14C succinato

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76546-1