Log In

Part Description

LP189526-9   Lysosomal acid lipase
Lysosomal acid lipase (LAL) is an enzyme that hydrolyzes cholesterol esters and triglycerides. Decreased levels of LAL leads to two autosomal recessive disorders known as Wolman disease (WD) and Cholesteryl Ester Storage Disease (CESD). Complete loss of the enzyme causes WD in infants who present with vomiting, diarrhea, poor weight gain and hepatomegaly subsequently leading to death. Partial loss of LAL causes CESD with variable symptoms ranging from asymptomatic to gastrointestinal symptoms, hepatomegaly, elevated transaminases and dyslipidemia. PMID: 25345094 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Lysosomal acid lipase:CCnt:Pt:Fibroblasts:Qn:4-MU-palmitate substrate
Long Common Name
Lysosomal acid lipase [Enzymatic activity/mass] in Fibroblast by 4-MU-palmitate substrate
Short Name
LAL Fib 4-MUP substrate-cCnt
Display Name
Lysosomal acid lipase 4-MU-palmitate substrate (Fibroblast) [Catalytic activity/Mass]
Consumer Name Alpha Get Info
Lysosomal acid lipase, Fibroblast

Part Model Get Info

  • Component
    Lysosomal acid lipase
    LP189526-9
    • Analyte
      Lysosomal acid lipase
      LP189526-9
      • Component Numerator
        Lysosomal acid lipase
        LP189526-9
        • Component Numerator Core
          Lysosomal acid lipase
          LP189526-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CCnt
    LP6790-2
  • Time
    Pt
    LP6960-1
  • System
    Fibroblasts
    LP7234-0
    • System Core
      Fibroblasts
      LP7234-0
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    4-MU-palmitate substrate
    LP189527-7

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
17095

Member of these Panels

LOINCLong Common Name
76621-2Lysosomal acid lipase panel - Fibroblast

Member of these Groups Get Info

LOINC GroupGroup Name
LG29985-5Lysosomal acid lipase|CCnt|Pt|Fibroblasts

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Lysozomální kyselá lipáza:Katalytický obsah:Časový bod:Fibroblast:Kvantitativní:Substrát 4-MU-palmitát
el-GRGreek (Greece)Λιπάση λυσοσωμικού οξέος:CCnt:Pt:Ινοβλάστες:Qn:4-MU-παλμιτικό υπόστρωμα
Synonyms: 4-MU-παλμιτικό υπόστρωμα CCnt CHEM Pt Qn Ινοβλάστες Λιπάση λυσοσωμικού οξέος
es-ESSpanish (Spain)Lipasa ácida lisosomal:Contenido catalítico:Punto temporal:Fibroblastos:Qn:Sustrato 4-MU-palmitato
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Lipasa ácida lisosomal:Contenido catalítico:Punto temporal:Fibroblasto:Cuantitativo:Sustrato de 4-MU-palmitato
fr-FRFrench (France)Lipase acide lysosomale:Catalytique/Masse:Ponctuel:Fibroblastes:Numérique:Substrat 4-MU-palmitate
it-ITItalian (Italy)Lipasi acida lisosomiale:CCnt:Pt:Fibroblasti:Qn:Substrato 4-Metilumbelliferiolo palmitato
Synonyms: Chimica Contenuto Catalitico Fibroblasto Punto nel tempo (episodio) Substrato 4-MU palmitato
nl-NLDutch (Netherlands)lysosomale zure lipase:enzymatische activiteit/massa:moment:fibroblast:kwantitatief:4-MU-palmitaatsubstraat
zh-CNChinese (China)溶酶体酸性脂肪酶:催化含量:时间点:成纤维细胞:定量型:4-MU-棕榈酸底物法
Synonyms: LAL;溶酶体酸性脂酶;溶酶体酸脂肪酶;溶酶体酸脂酶 催化含量(单位质量);单位质量的酶单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 纤维原细胞;纤维母细胞 酸

Example Units

UnitSource
nmol/h/mg{protein}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76615-4