Version 2.71

77137-8Bilirubin.total [Moles/volume] in Serum, Plasma or BloodActive

Part Description

LP15448-1   Bilirubin
Bilirubin is an orange-yellow pigment produced by the normal breakdown of heme, a component of the hemoglobin found in red blood cells. It is processed by the liver and excreted in bile. Conditions that cause red blood cell breakdown or interfere with liver or bile processing can cause elevated levels of bilirubin. Bilirubin exists in many forms. Non-glucuronidated bilirubin (also called unconjugated or indirect) is the breakdown product of heme and is not water-soluble. Hemolytic anemias, which cause increased red blood cell breakdown, are one cause of elevated non-glucuronidated bilirubin. Glucuronidated bilirubin (also called conjugated) is a water-soluble form of bilirubin that is made in the liver by the addition of sugar molecules to non-glucuronidated bilirubin. Conditions that affect liver function (such as hepatitis, cirrhosis and liver tumors) or physically block the bile ducts (such as gallstones) can cause elevated levels of glucuronidated bilirubin. A third form of bilirubin is that which is bound to albumin, and it is also known as delta bilirubin because it was originally identified based on the unexpected difference between the total bilirubin level and the level of glucuronidated plus non-glucuronidated bilirubin in some patient samples. Prior to the discovery of albumin-bound bilirubin, the term "direct" bilirubin was used as a synonym for glucuronidated bilirubin, but direct bilirubin is actually glucuronidated plus delta bilirubin (bilirubin covalently bound to albumin). Source: Regenstrief LOINC

Fully-Specified Name


Additional Names

Short Name
Bilirub SerPlBld-sCnc
Display Name
Bilirubin (S/P/Bld) [Moles/Vol]
Consumer Name Alpha
Bilirubin, Blood

Basic Attributes

First Released
Version 2.52
Last Updated
Version 2.68
Change Reason
Release 2.68: DefinitionDescription: Moved to Mapping Guidance section.
Order vs. Observation

Reference Information

Type Source Reference
Mapping Guidance LOINCCopyright Copyright © 2001-2019 American Association for Clinical Chemistry This term was made to accommodate a laboratory system outside of the US. LOINC currently discourages the use of specimens combining ser/plas and blood in one term (as ser/plas/bld) for two reasons. First, practices usually want to distinguish the two on ordering since whole blood usually implies a point of care test and ser/plas usually implies sending to another location. Second, whole blood tests are usually classified as low complexity (waived) under CLIA regulations, and because waived tests are excluded from the annual COLA report of testing volume (required by the Centers for Medicare and Medicaid Services) and ser/plas tests are not, the two have to be distinguished. Bilirubin
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Bilirubin

Member of these Groups

LG2811-0 Bilirubin|SCnc|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
nl-NLDutch (Netherlands)
bilirubine:mol/volume:moment:serum of plasma of bloed:kwantitatief:
et-EEEstonian (Estonia)
fr-BEFrench (Belgium)
Bilirubine:Concentration de substance:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-CAFrench (Canada)
Bilirubine:Concentration de substance:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-FRFrench (France)
it-ITItalian (Italy)
ru-RURussian (Russian Federation)
es-ESSpanish (Spain)
Bilirrubina:Concentración de sustancia:Punto temporal:Suero, Plasma o Sangre:Qn:
tr-TRTurkish (Turkey)

Example Units

Unit Source
umol/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info