77141-0

Alkaline phosphatase [Enzymatic activity/volume] in Serum, Plasma or Blood

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Part Descriptions

LP15346-7 Alkaline phosphatase
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1. Source: National Library of Medicine, MeSH 2006

LP15346-7 Alkaline phosphatase
Alkaline phosphatase (ALP, ALKP) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. ALP is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. Humans and most other mammals contain the following ALP isozymes: ALPI (intestinal), ALPL (tissue non-specific, liver/bone/kidney), and ALPP (placental, aka Regan isozyme).

The normal range of alkaline phosphatase is 20 to 140 IU/L. High ALP levels are present in children and pregnant women, if bile ducts are blocked, and in the presence of osteoblast activity, such as with Paget's disease of the bone. Lowered levels of ALP are less common than elevated levels and occurs in various conditions, including aplastic and pernicious anemias, chronic myelogenous leukemia, Wilson's disease, children with severe enteritis, and postmenopausal women on estrogen therapy for osteoporosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Alkaline phosphatase (Wikipedia)

Reference Information

Type	Source	Reference
Mapping Guidance	LOINC	This term was made to accommodate a laboratory system outside of the US. LOINC currently discourages the use of specimens combining ser/plas and blood in one term (as ser/plas/bld) for two reasons. First, practices usually want to distinguish the two on ordering since whole blood usually implies a point of care test and ser/plas usually implies sending to another location. Second, whole blood tests are usually classified as low complexity (waived) under CLIA regulations, and because waived tests are excluded from the annual COLA report of testing volume (required by the Centers for Medicare and Medicaid Services) and ser/plas tests are not, the two have to be distinguished.

LOINC Names Get Info

Fully-Specified Name: Alkaline phosphatase:CCnc:Pt:Ser/Plas/Bld:Qn:
Long Common Name: Alkaline phosphatase [Enzymatic activity/volume] in Serum, Plasma or Blood
Short Name: ALP SerPlBld-cCnc
Display Name: ALP (S/P/Bld) [Catalytic activity/Vol]
Consumer Name Alpha Get Info: Alkaline phosphatase, Blood

Part Model Get Info

Component
Alkaline phosphatase
LP15346-7
- Analyte
  Alkaline phosphatase
  LP15346-7
  - Component Numerator
    Alkaline phosphatase
    LP15346-7
    - Component Numerator Core
      Alkaline phosphatase
      LP15346-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
CCnc
LP6789-4
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas/Bld
LP7579-8
- System Core
  Ser/Plas/Bld
  LP7579-8
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.52
Last Updated: Version 2.73 (MIN)
Change Reason: Release 2.68: DefinitionDescription: Moved to Mapping Guidance section.
Order vs. Observation: Both
Common Test Rank Get Info: 9179

Member of these Groups Get Info

LOINC Group	Group Name
LG5665-7	Alkaline phosphatase\|CCnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Alkalická fosfatáza:Katalytická koncentrace:Časový bod:Sérum/plazma/krev:Kvantitativní:
el-GR	Greek (Greece)	Αλκαλική φωσφατάση:CCnc:Pt:Ορός/Πλάσμα/Αίμα:Qn: Synonyms: CCnc CHEM Pt Qn Αίμα Αλκαλική φωσφατάση Ορός Ορός/Πλάσμα Ορός/Πλάσμα/Αίμα Πλάσμα Πλάσμα/Αίμα
es-ES	Spanish (Spain)	Fosfatasa alcalina total:Concentración Catalítica:Punto temporal:Suero, Plasma o Sangre:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Fosfatasa alcalina:Concentración catalítica:Punto temporal:Suero, plasma o sangre:Cuantitativo:
et-EE	Estonian (Estonia)	Aluseline fosfataas:CCnc:Pt:S/P/B:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma Seerum või plasma või veri Veri
fr-CA	French (Canada)	Phosphatase alcaline:Concentration catalytique:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-FR	French (France)	Phosphatases alcalines:Catalytique/Volume:Ponctuel:Sérum/Plasma/Sang:Numérique:
fr-BE	French (Belgium)	Phosphatase alcaline:Concentration catalytique:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif: Synonyms: ALP
it-IT	Italian (Italy)	Fosfatasi alcalina:CCnC:Pt:Siero/Plasma/Sangue,Siero,Plasma o Sangue:Qn: Synonyms: Chimica Concentrazione Catalitica Plasma Plasma o Sangue Punto nel tempo (episodio) Sangue Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	alkalische fosfatase:enzymatische activiteit/volume:moment:serum of plasma of bloed:kwantitatief:
pl-PL	Polish (Poland)	Fosfataza zasadowa:stężenie katalityczne:punkt w czasie:surowica, osocze lub krew:ilościowy: Synonyms: osocze lub krew
ru-RU	Russian (Russian Federation)	Щелочная фосфатаза:КаталКонц:ТчкВрм:Сыв/Плаз/Кр:Колич: Synonyms: Каталитическая концентрация Количественный Кровь Плазма Сыворотка Сыворотка или Плазма Сыворотка, Плазма или Кровь Точка во времени;Момент
tr-TR	Turkish (Turkey)	Alkalen fosfataz:KtlKons:Zmlı:Ser/Plaz/Kan:Kant:
uk-UA	Ukrainian (Ukraine)	Лужна фосфатаза:Каталітична Концентрація:МоментЧасу:Сироватка/Плазма/Кров:Кількісно: Synonyms: Alk; Alk phos; Alkaline phos; Alkaline phosphatase.total; ALKP; ALP; AP; Blood; Catalytic Concentration; Chemistry; Hepatology; LimitedUseLabOrders; Liver; MSK; Musculoskeletal; Ortho; Orthopedics; Phos; Phosphtase; Pl; PlasBld; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; SerPlBld; Serum; Serum or plasma; Serum, plasma or whole blood; SR; WB; Whole blood
zh-CN	Chinese (China)	碱性磷酸酶:催化浓度:时间点:血清/血浆/全血:定量型: Synonyms: ALKP;ALP;AP;总碱性磷酸酯酶;总碱性磷酸酶;总碱磷酶;碱性磷酸酯酶;碱性磷酸酯酶.总计;碱性磷酸酶.总计;碱磷酶;碱磷酶.总计催化浓度(单位体积);单位体积内酶的单位数化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间碱磷酸单酯酶磷酸酶血;血液血浆或全血;血浆/血液;血浆或血液血清、血浆或全血;血清、血浆或血液;血清/血浆/血液血清或血浆

Example Units

Unit	Source
U/L	Example UCUM Units

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