Version 2.77

Descriptions

An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1. Source: National Library of Medicine, MeSH 2006

Alkaline phosphatase (ALP, ALKP) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. ALP is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. Humans and most other mammals contain the following ALP isozymes: ALPI (intestinal), ALPL (tissue non-specific, liver/bone/kidney), and ALPP (placental, aka Regan isozyme).

The normal range of alkaline phosphatase is 20 to 140 IU/L. High ALP levels are present in children and pregnant women, if bile ducts are blocked, and in the presence of osteoblast activity, such as with Paget's disease of the bone. Lowered levels of ALP are less common than elevated levels and occurs in various conditions, including aplastic and pernicious anemias, chronic myelogenous leukemia, Wilson's disease, children with severe enteritis, and postmenopausal women on estrogen therapy for osteoporosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Alkaline phosphatase (Wikipedia)

Basic Part Properties

Part Display Name
Alkaline phosphatase
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
ALP

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15346-7

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 碱性磷酸酶
Synonyms: ALKP;ALP;AP;总碱性磷酸酯酶;总碱性磷酸酶;总碱磷酶;碱性磷酸酯酶;碱性磷酸酯酶.总计;碱性磷酸酶.总计;碱磷酶;碱磷酶.总计
fr-CA French (Canada) Phosphatase alcaline
et-EE Estonian (Estonia) Aluseline fosfataas
es-ES Spanish (Spain) Fosfatasa alcalina total
it-IT Italian (Italy) Fosfatasi alcalina
el-GR Greek (Greece) Αλκαλική φωσφατάση
Synonyms: ALP
tr-TR Turkish (Turkey) Alkalen fosfataz
ru-RU Russian (Russian Federation) Щелочная фосфатаза
nl-NL Dutch (Netherlands) alkalische fosfatase
fr-BE French (Belgium) Phosphatase alcaline
Synonyms: ALP
pl-PL Polish (Poland) Fosfataza zasadowa