Version 2.67

77210-3Salivary gland protein 1 IgG Ab [Units/volume] in Serum by ImmunoassayActive

Part Description

LP189704-2   Salivary gland protein 1 Ab.IgG
Salivary gland protein 1 (SP-1) antibodies may be useful markers for identifying patients with Sjogren's disease or Sjogren's syndrome early in the course of disease and those who have significant symptoms but are anti-Ro and anti-La antibody negative. Sjogren's disease is an autoimmune disease associated with kidney and lung disease as well as disorders of the salivary and lacrimal glands, which lead to problems with dry eyes and mouth. Sjogren's syndrome is associated with isolated salivary and lacrimal gland dysfunction and may be associated with other autoimmune disorders, such as systemic lupus erythematosus. Both the disease and syndrome are typically diagnosed later in the disease course due to non-specific or mild symptoms early in the course. SP-1 has been identified in mice based on mRNA expression in submandibular and lacrimal glands; although human SP-1 has not been isolated to date and its function is unknown, SP-1 antibodies have been identified as a specific marker in Sjogren's patients. [PMID: 23123440] Copyright Copyright 2001-2019 American Association for Clinical Chemistry. Source: Regenstrief LOINC, PMID: 23123440

Fully-Specified Name

Salivary gland protein 1 Ab.IgG

Additional Names

Short Name
SP-1 IgG Ser IA-aCnc
Display Name
Salivary gland protein 1 IgG IA Qn (S)

Basic Attributes

First Released
Version 2.52
Last Updated
Version 2.56
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Member of these Panels

LOINC Long Common Name
77217-8 Salivary gland protein 1 and Carbonic anhydrase 6 and Parotid secretory protein IgA and IgG and IgM panel - Serum by Immunoassay

Language Variants Get Info

zh-CNChinese (CHINA)
唾液腺蛋白 1 抗体.IgG:任意型浓度:时间点:血清:定量型:免疫测定法
speekselklier proteïne 1 As.IgG:eenheid/volume:moment:serum:kwantitatief:immunoassay
fr-FRFrench (FRANCE)
Salivary gland protein 1 Ab.IgG:ACnc:Pt:Ser:Qn:IA
it-ITItalian (ITALY)
Ghiandola salivare, proteina 1 , Ab.IgG:ACnc:Pt:Siero:Qn:IA
es-ESSpanish (SPAIN)
Proteína de las glándulas salivales IgG:Concentración arbitraria:Punto temporal:Suero:Qn:IA
tr-TRTurkish (TURKEY)
Tükrük bezi protein 1 Ab.IgG:SçKons:Zmlı:Ser:Kant:İA

Example Units

Unit Source
{ELISA'U}/mL Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info