Version 2.67

77213-7Carbonic anhydrase 6 IgM Ab [Units/volume] in Serum by ImmunoassayActive

Part Description

LP189706-7   Carbonic anhydrase 6 Ab.IgM
Carbonic anhydrase 6 (CA6) antibodies are early markers for identifying patients with Sjogren's disease or Sjogren's syndrome and may identify those who have significant symptoms but are anti-Ro and anti-La antibody negative. Sjogren's disease is an autoimmune disease associated with kidney and lung disease as well as disorders of the salivary and lacrimal glands, which lead to problems with dry eyes and mouth. Sjogren's syndrome is associated with isolated salivary and lacrimal gland dysfunction and may be associated with other autoimmune disorders, such as systemic lupus erythematosus. Both the disease and syndrome are typically diagnosed later in the disease course due to non-specific or mild symptoms early in the course. CA6 is an enzyme that is found in the submandibular and parotid glands and is involved in the buffering capacity of saliva. CA6 antibodies occur early in the course of Sjogren's disease and are almost always found in patients who also have salivary gland protein 1 antibodies. CA6 antibodies rarely occur in patients without autoimmune disease or those with autoimmune disease who do not have problems with dry eyes and mouth. [PMID: 23123440] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, PMID: 23123440

Fully-Specified Name

Carbonic anhydrase 6 Ab.IgM

Additional Names

Short Name
CA6 IgM Ser IA-aCnc
Display Name
Carbonic anhydrase 6 IgM IA Qn (S)

Basic Attributes

First Released
Version 2.52
Last Updated
Version 2.56
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Member of these Panels

LOINC Long Common Name
77217-8 Salivary gland protein 1 and Carbonic anhydrase 6 and Parotid secretory protein IgA and IgG and IgM panel - Serum by Immunoassay

Language Variants Get Info

zh-CNChinese (CHINA)
碳酸酐酶 6 抗体.IgM:任意型浓度:时间点:血清:定量型:免疫测定法
carbonaatanhydrase 6 As.IgM:eenheid/volume:moment:serum:kwantitatief:immunoassay
fr-FRFrench (FRANCE)
Anhydrase carbonique 6 anticorps IgM:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
it-ITItalian (ITALY)
Anidrasi carbonica 6 , Ab.IgM:ACnc:Pt:Siero:Qn:IA
es-ESSpanish (SPAIN)
Anhidrasa carbónica 6 IgM:Concentración arbitraria:Punto temporal:Suero:Qn:IA
tr-TRTurkish (TURKEY)
Karbonik anhidrz 6 Ab.IgM:SçKons:Zmlı:Ser:Kant:İA

Example Units

Unit Source
{ELISA'U}/mL Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info