Version 2.77

Part Description

LP15392-1   Anion gap 4
Anion Gap 4 is the difference between the sum of serum sodium + serum potasium and the sum of the serum bicarbonate+ chloride. Calculated based on the concentration of four electrolytes as follows: ([Na+] + [K+]) − ([Cl−] + [HCO3−]). An increased gap indicates the presence of an unmeasured anion. Source: Regenstrief Institute

Reference Information

Type Source Reference
Mapping Guidance LOINC This term was made to accommodate a laboratory system outside of the US. LOINC currently discourages the use of specimens combining ser/plas and blood in one term (as ser/plas/bld) for two reasons. First, practices usually want to distinguish the two on ordering since whole blood usually implies a point of care test and ser/plas usually implies sending to another location. Second, whole blood tests are usually classified as low complexity (waived) under CLIA regulations, and because waived tests are excluded from the annual COLA report of testing volume (required by the Centers for Medicare and Medicaid Services) and ser/plas tests are not, the two have to be distinguished.

Fully-Specified Name

Component
Anion gap 4
Property
SCnc
Time
Pt
System
Ser/Plas/Bld
Scale
Qn
Method

Additional Names

Short Name
Anion Gap4 SerPlBld-sCnc
Display Name
Anion gap 4 (S/P/Bld) [Moles/Vol]
Consumer Name Alpha Get Info
Anion gap 4, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.68
Change Reason
Release 2.68: DefinitionDescription: Moved to Mapping Guidance section.; Previous Releases: Changed the method from "Calculated" to methodless to fit the current LOINC model.
Order vs. Observation
Observation

Formula (Readable)

(NA+K) - (CL+CO2)=Anion Gap

Member of these Groups Get Info

LOINC Group Group Name
LG6139-2 Anion gap 4|SCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Anión GAP 4:Concentración de sustancia:Punto temporal:Suero, Plasma o Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Brecha aniónica 4:Concentración de sustancias:Punto temporal:Suero, plasma o sangre:Cuantitativo:
et-EE Estonian (Estonia) Anioonide vahe 4:SCnc:Pt:S/P/B:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma Seerum või plasma või veri Veri
fr-CA French (Canada) Trou anionique 4:Concentration de substance:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-FR French (France) Balance ionique 4:Moles/Volume:Ponctuel:Sérum/Plasma/Sang:Numérique:
fr-BE French (Belgium) Trou anionique 4:Concentration de substance:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
it-IT Italian (Italy) Gap anionico 4:SCnc:Pt:Siero/Plasma/Sangue:Qn:
Synonyms: Chimica Concentrazione di Sostanza Plasma Plasma o Sangue Punto nel tempo (episodio) Sangue Siero Siero o Plasma Siero,Plasma o Sangue
nl-NL Dutch (Netherlands) anion gap 4:mol/volume:moment:serum of plasma of bloed:kwantitatief:
ru-RU Russian (Russian Federation) Анионный интервал 4:МолКонц:ТчкВрм:Сыв/Плаз/Кр:Колич:
Synonyms: Анионный промежуток Анионный промежуток 4 Количественный Кровь Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Сыворотка, Плазма или Кровь Точка во времени;Момент
tr-TR Turkish (Turkey) Anyon açığı 4:SubKons:Zmlı:Ser/Plaz/Kan:Kant:
Synonyms: Anyon gap Anyon gap 4
zh-CN Chinese (China) 阴离子间隙 4:物质的量浓度:时间点:血清/血浆/全血:定量型:
Synonyms: [(NA+)]-[(Cl-)+(CO2-)]+K;AG4;四变量型负离子缺额;四变量型负离子间隙;四变量型负离子隙;四变量型阴离子间隙;四变量型阴离子隙;负离子缺额 4;负离子间隙 4;负离子隙 4;阴离子隙 4 AG;AG (K+);AnGAP;负离子缺额;负离子间隙;负离子隙;阴离子间隙 (K+);阴离子间隙（Anion Gap，AG）;阴离子隙 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血;血液 血浆或全血;血浆/血液;血浆或血液 血清、血浆或全血;血清、血浆或血液;血清/血浆/血液 血清或血浆

Example Units

Unit Source
mmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77341-6