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Part Descriptions

LP182372-5   Diploid G1 phase cell population peak channel
DNA index (DI), which is associated with DNA ploidy, is a reflection of the average amount of DNA in the tumor cells. The DI can be measured by flow cytometry or image cytometry, both of which result in a DNA ploidy histogram, where the channel number on the x-axis represents fluorescent intensity or optical density for the two methods, respectively. All cells with the same quantity of DNA form one peak on the histogram, and with a population of normal cells, the largest peak represents diploid cells in G1 of the cell cycle, and a smaller peak represents cells in G2/M-phase. When there is a mixed population of normal and tumor cells, two or more G1 peaks will be seen, one for the normal cells and one or more for the tumor cells. The DI is calculated by dividing the channel number of the tumor cell G1 peak by the channel number of the normal (diploid control) G1 peak. If the tumor cells are diploid, the DI is 1, and if the cells are aneuploid, the DI is greater than or less than 1. For example, tetraploid cells have a DI of 2 because they have twice as much DNA content as normal diploid cells, and hypodiploid tumor cells have a DI of <1. PMID: 24532190 Source: Regenstrief LOINC, PMID: 24532190

LP182372-5   Diploid G1 phase cell population peak channel
Cell cycle DNA analysis is used to quantify the number of cells in various phases of the cell cycle. Tumor cell cycle analysis can be used to assess the proliferative potential of the tumor, which in some types of cancer can be used as a prognostic indicator. G0 is a quiescent phase during which cells are metabolically active but no longer proliferate unless called on to do so by appropriate extracellular signals. The G1 phase is the interval between mitosis and start of DNA replication during which the cell is metabolically active and continuously grows but does not replicate its DNA. G1 is followed by the S phase, during which DNA replication occurs. G2 follows S, and during G2 the cell continues to grow and synthesize proteins in preparation for mitosis. The M phase of the cycle corresponds to mitosis, during which the cell divides. [NCBI Books: NBK9876] Source: Regenstrief LOINC, NCBI Books: NBK9876

LOINC Names Get Info

Fully-Specified Name
Diploid G1 phase cell population peak channel:Num:Pt:Cells.XXX:Qn:Flow cytometry
Long Common Name
Diploid G1 phase cell population peak channel [#] in Cells.XXX by Flow cytometry (FC)
Short Name
Diploid G1 peak chan Cells.XXX FC
Display Name
Diploid G1 phase cell population peak channel FC (Unsp Cells) [#]
Consumer Name Alpha Get Info
Diploid G1 Phase Cell Population Peak Channel, Unspecified Cells

Part Model Get Info

  • Component
    Diploid G1 phase cell population peak channel
    LP182372-5
    • Analyte
      Diploid G1 phase cell population peak channel
      LP182372-5
      • Component Numerator
        Diploid G1 phase cell population peak channel
        LP182372-5
        • Component Numerator Core
          Diploid G1 phase cell population peak channel
          LP182372-5
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Num
    LP6841-3
  • Time
    Pt
    LP6960-1
  • System
    Cells.XXX
    LP100478-9
  • Scale
    Qn
    LP7753-9
  • Method
    Flow cytometry
    LP6274-7

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.52 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Diploidní buněčná populace G1 fáze kanál s populačním vrcholem:Počet:Časový bod:Buňky.XXX:Kvantitativní:Průtoková cytometrie
el-GRGreek (Greece)Κανάλι αιχμής πληθυσμού διπλοειδών κυττάρων φάσης G1:Αρ.:Pt:Κύτταρα.XXX:Qn:Κυτταρομετρία ροής
Synonyms: MOLPATH Pt Qn XXX Αρ. Κανάλι αιχμής πληθυσμού διπλοειδών κυττάρων φάσης G1 Κύτταρα.XXX Κυτταρομετρία ροής
es-ESSpanish (Spain)pico población celular diploide en fase G1:Número (recuento):Punto temporal:Células XXX:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Canal de pico de población de células de fase diploide G1:Número (recuento):Punto temporal:Cells.XXX:Cuantitativo:Citometría de flujo (FC)
fr-FRFrench (France)Cellules diploïdes en phase G1 pic de population:Nombre:Ponctuel:Cellules XXX:Numérique:Cytométrie de flux
it-ITItalian (Italy)Fase G1 popolazione cellulare diploide, canale di picco:Num:Pt:Cellule.XXX:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Numero (conta) Patologia molecolare Punto nel tempo (episodio)
nl-NLDutch (Netherlands)diploïd G1 fase cel populatie piek kanaal:aantal:moment:cellen.XXX:kwantitatief:flowcytometrie
pl-PLPolish (Poland)Komórki diploidalne fazy G1 w kanale szczytowym:liczba:punkt w czasie:komórki.XXX:ilościowy:cytometria przepływowa (FC)
Synonyms: Komórki diploidalne fazy G1 w kanale szczytowym
tr-TRTurkish (Turkey)Diploid G1 fazı hücre popülasyonu tepe kanalı:Say:Zmlı:Hücreler.XXX:Kant:Akış sitometri
Synonyms: Akış hücremetresi
zh-CNChinese (China)二倍体 G1 期细胞总体峰值通道:数量(计数):时间点:细胞.XXX:定量型:流式细胞测量术
Synonyms: XXX细胞;此处不作说明的细胞;细胞.此处不作说明的;此处未作说明的细胞 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 个数;数量;数量或计数（非负整数）;计数 二倍体（双倍体、倍数染色体、双重、双倍） G1 期（相）细胞总体（统计总体、总数、群体总数、群体）峰值通道（峰值通道数、峰值道数、道峰值、道峰） 分子病理学;分子病理学试验 动态 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计

Example Units

UnitSource
{#}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77662-5