Version 2.80

Part Descriptions

LP182373-3   Aneuploid G1 phase cell population peak channel
DNA index (DI), which is associated with DNA ploidy, is a reflection of the average amount of DNA in the tumor cells. The DI can be measured by flow cytometry or image cytometry, both of which result in a DNA ploidy histogram, where the channel number on the x-axis represents fluorescent intensity or optical density for the two methods, respectively. All cells with the same quantity of DNA form one peak on the histogram, and with a population of normal cells, the largest peak represents diploid cells in G1 of the cell cycle, and a smaller peak represents cells in G2/M-phase. When there is a mixed population of normal and tumor cells, two or more G1 peaks will be seen, one for the normal cells and one or more for the tumor cells. The DI is calculated by dividing the channel number of the tumor cell G1 peak by the channel number of the normal (diploid control) G1 peak. If the tumor cells are diploid, the DI is 1, and if the cells are aneuploid, the DI is greater than or less than 1. For example, tetraploid cells have a DI of 2 because they have twice as much DNA content as normal diploid cells, and hypodiploid tumor cells have a DI of <1. PMID: 24532190 Source: Regenstrief LOINC , PMID: 24532190

LP182373-3   Aneuploid G1 phase cell population peak channel
Cell cycle DNA analysis is used to quantify the number of cells in various phases of the cell cycle. Tumor cell cycle analysis can be used to assess the proliferative potential of the tumor, which in some types of cancer can be used as a prognostic indicator. G0 is a quiescent phase during which cells are metabolically active but no longer proliferate unless called on to do so by appropriate extracellular signals. The G1 phase is the interval between mitosis and start of DNA replication during which the cell is metabolically active and continuously grows but does not replicate its DNA. G1 is followed by the S phase, during which DNA replication occurs. G2 follows S, and during G2 the cell continues to grow and synthesize proteins in preparation for mitosis. The M phase of the cycle corresponds to mitosis, during which the cell divides. [NCBI Books: NBK9876] Source: Regenstrief LOINC , NCBI Books: NBK9876

Fully-Specified Name

Component
Aneuploid G1 phase cell population peak channel
Property
Num
Time
Pt
System
Cells.XXX
Scale
Qn
Method
Flow cytometry

Additional Names

Long Common Name
Aneuploid G1 phase cell population peak channel [#] in Cells.XXX by Flow cytometry (FC)
Short Name
Aneu G1 pop peak chan Cells.XXX FC
Display Name
Aneuploid G1 phase cell population peak channel FC (Unsp Cells) [#]
Consumer Name Alpha Get Info
Aneuploid G1 Phase Cell Population Peak Channel, Unspecified Cells

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.52 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κανάλι αιχμής πληθυσμού ανευπλοειδών κυττάρων φάσης G1:Αρ.:Pt:Κύτταρα.XXX:Qn:Κυτταρομετρία ροής
Synonyms: Αρ. Κανάλι αιχμής πληθυσμού ανευπλοειδών κυττάρων φάσης G1
es-ES Spanish (Spain) pico población celuar aneuploide en fase G1:Número (recuento):Punto temporal:Células XXX:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Canal de pico de población de células de fase aneuploide G1:Número (recuento):Punto temporal:Cells.XXX:Cuantitativo:Citometría de flujo (FC)
fr-FR French (France) Cellules aneuploïdes en phase G1 pic de population:Nombre:Ponctuel:Cellules XXX:Numérique:Cytométrie de flux
it-IT Italian (Italy) Fase G1 popolazione cellulare aneuploide, canale di picco:Num:Pt:Cellule.XXX:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Numero (conta) Patologia molecolare Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) aneuploïd G1 fase celpopulatie piek kanaal:aantal:moment:cellen.XXX:kwantitatief:flowcytometrie
pl-PL Polish (Poland) Aneuploidalne komórki populacji w fazie G1, piki w kanale:liczba:punkt w czasie:komórki XXX:ilościowy:cytometria przepływowa (FC)
Synonyms: Piki w kanale dla populacji komórek aneuploidalnych w fazie G1
tr-TR Turkish (Turkey) Aneuploid G1 fazı hücre popülasyonu tepe kanalı:Say:Zmlı:Hücreler.XXX:Kant:Akış sitometri
Synonyms: Akış hücremetresi
zh-CN Chinese (China) 非整倍体 G1 期细胞总体峰值通道:数量(计数):时间点:细胞.XXX:定量型:流式细胞测量术
Synonyms: XXX细胞;此处不作说明的细胞;细胞.此处不作说明的;此处未作说明的细胞 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 个数;数量;数量或计数（非负整数）;计数 分子病理学;分子病理学试验 动态 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 异倍体（非整倍体、异倍、非整倍） G1 期（相）细胞总体（统计总体、总数、群体总数、群体）峰值通道（峰值通道数、峰值道数、道峰值、道峰） 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计

Example Units

Unit Source
{#} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77663-3