77763-1

ALPRAZolam cutoff [Mass/volume] in Saliva (oral fluid) for Confirmatory method

Active

Part Descriptions

LP14981-2   ALPRAZolam
Alprazolam (brand name Xanax) is a short-acting anxiolytic of the benzodiazepine class of psychoactive drugs, used to treat anxiety and panic disorders. It works by binding to gamma aminobutyric acid (GABA) receptors in the brain to increase GABA-mediated synaptic inhibition. Alprazolam is also sometimes used to treat depression, fear of open spaces (agoraphobia), and premenstrual syndrome. Alprazolam can be habit-forming and some of the more serious potential side effects are: shortness of breath, seizures, hallucinating, severe skin rash, yellowing of the skin or eyes, depression, memory problems, confusion, problems with speech, unusual changes in behavior or mood, and suicidal thoughts. Source: Regenstrief LOINC, MedlinePlus: a684001

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name

ALPRAZolam cutoff:MCnc:Pt:Saliva:Qn:Confirm

Long Common Name

ALPRAZolam cutoff [Mass/volume] in Saliva (oral fluid) for Confirmatory method

Short Name

Alpraz CtO Sal Cfm-mCnc

Display Name

ALPRAZolam cutoff Confirm (Sal) [Mass/Vol]

Consumer Name Alpha Get Info

ALPRAZolam cutoff, Saliva

Part Model Get Info

• Component

  ALPRAZolam cutoff
  LP227590-9

  • Analyte

    ALPRAZolam cutoff
    LP227590-9

    • Component Numerator

      ALPRAZolam cutoff
      LP227590-9

      • Component Numerator Core

        ALPRAZolam
        LP14981-2

      • Component Numerator Core Suffix

        cutoff
        LP29252-1

    • Component Denominator

      NULL
       

      • Component Denominator Core

        NULL
         

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  MCnc
  LP6827-2

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  Saliva
  LP7565-7

  • System Core

    Saliva
    LP7565-7

  • Super System

    NULL
     

• Scale

  Qn
  LP7753-9

• Method

  Confirm
  LP6197-0

Basic Attributes

Class

DRUG/TOX

Type

Laboratory

First Released

Version 2.52

Last Updated

Version 2.52 (MIN)

Order vs. Observation

Observation

Language Variants Get Info

Related Names

• Cfm
• CNFR
• CNFRM
• Conf
• Confirmation
• Confirmatory
• CtO
• DRUG/TOXICOLOGY
• Drugs
• GCMS
• LC/MS/MS
• Level
• Mass concentration
• Niravam
• Oral fluid
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Sal
• Xanax

Example Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77763-1

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.