78019-7
Toscana virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
Active
Term Description
Because Toscana virus is a known etiologic agent of meningitis, meningoencephalitis, and encephalitis, cerebrospinal fluid (CSF) may be tested. Specific antibodies for IgM are present during the acute phase of the Toscana Virus infection, while the presence of specific IgG antibodies in the absence of IgM indicates a previous infection. Cross reactions cannot be excluded with other correlated serotypes of Phlebovirus such as Sicily and Naples. This term was created for, but not limited in use to, the submitter's Diesse ENZYWELL TOSCANA VIRUS IgG/IgM test kit.
Source: Regenstrief LOINC
Part Descriptions
LP190786-6 Toscana virus
Toscana virus (TOSV) was identified in 1971 in central Italy from sandflies Phlebotomus perniciosus and Phlebotomus perfiliewi PMID: 24175218. TOSV belongs to the family Phenuiviridae, genus Phlebovirus [NCBI Taxonomy: 11590)]. TOSV is a serotype of the species Sandfly fever Naples virus PMID: 24175218. TOSV is the only neurotropic sandfly phlebovirus typically causing meningitis and encephalitis. Additional neuroinvasive manifestations such as Guillain-Barré syndrome, hydrocephalus, myositis, fasciitis, polymyeloradiculopathy, deafness, and facial paralysis, have been reported. Toscana virus broadly circulates in in European Mediterranean basin and Northern Africa PMID: 32878929.
Source: Regenstrief LOINC
LP190786-6 Toscana virus
The Toscana virus (TOSV) belongs to the Bunyaviridae family whose genome is made of three negative single-stranded RNA segments. There are two genotypes of TOSV: A, found mainly in Italy, and B, occurring mainly in Spain. The distribution of the two genotypes may indicate the involvement of different vectors. Infection by TOSV is most prevalent in Italy and Spain in the summer months, though the geographical region where TOSV is expanding includes other countries in the Mediterranean basin. TOSV is transmitted to humans by the Phlebotomus species of sandflies. Though the animal reservoir has not been identified, TOSV has been isolated from the brain of a bat, which raises the question of it possibly being a host to the virus. TOSV causes aseptic meningitis in 95% of the people it infects, meningoencephalitis in 4.5% of those infected, and an influenza-like illness in the remaining .5% who are infected. Recently, unusual symptoms associated with TOSV have included ischemic complications and hydrocephalus. TOSV is emerging as an important pathogen as its distribution increases due to changes in the climate, globalization and habitat modification. Other than supportive therapy, there is no treatment for infection with TOSV. PMID: 20517492
Source: Regenstrief LOINC
LP190787-4 Toscana virus Ab.IgM
The Toscana virus (TOSV) belongs to the Phlebovirus genus of the Bunyaviridae family, and is an arthropod-borne virus transmitted to humans by Phlebotomus spp sandflies. The Toscana virus infection is characterized by fever, strong headache, and meningitis, or meningoencephalitis. TOSV is the major cause of aseptic meningitis (95%) and meningoencephalitis (4.5%) and influenza-like illness during the summer season. Some unusual clinical manifestations due to TOSV with severe sequelae, such as ischemic complications and hydrocephalus, have been reported. TOSV represents an important emerging pathogen and it is being investigated in several countries on the Mediterranean basin, including Italy, France, Spain, Portugal and Cyprus. Phylogenetic analysis has distinguished two genotypes of TOSV, A and B. The first is circulating mainly in Italy and the second in Spain, indicating a different geographic distribution possibly related to the vector. There is no treatment for TOSV infection except for supportive therapy. PMID: 20517492
Source: Regenstrief LOINC, PMID: 20517492
Fully-Specified Name
- Component
- Toscana virus Ab.IgM
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- TOSV IgM CSF Ql IA
- Display Name
- Toscana virus IgM IA Ql (CSF)
- Consumer Name Alpha Get Info
- Toscana virus IgM antibody, Spinal fluid
Example Answer List: LL2010-8
Source: Estonian Society of Laboratory Medicine| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Borderline | LA4259-3 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Toskana-Virus Ak.IgM: Synonyms: TOS; |
| es-ES | Spanish (Spain) | Virus Toscana IgM: |
| es-MX | Spanish (Mexico) | Ab.IgM del virus de Toscana: |
| fr-FR | French (France) | Toscana virus Ac IgM: |
| it-IT | Italian (Italy) | Virus Toscana Ab.IgM: Synonyms: Anticorpi IgM anticorpo Immunoassay Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | Toscana virus As.IgM: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Wirus gorączki wywołanej przez muchę piaskową typ toskański Ab.IgM: Synonyms: IgM Przeciwciała do toskańskiego typu wirusa gorączki wywołanej przez muchę piaskową Przeciwciała IgM do toskańskiego typu wirusa gorączki wywołanej przez muchę piaskową Toskański typ wirusa gorączki wywołanej przez muchę piaskową |
| tr-TR | Turkish (Turkey) | Toscana virüs Ab.IgM: Synonyms: Ak Ak.IgM İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | 托斯卡纳病毒 抗体.IgM: Synonyms: Ab.IgM; |
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