78211-0

Cells.4q12 chromosome region rearrangements/Cells counted in Blood or Tissue by FISH

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Part Descriptions

LP190794-0 Cells.4q12 chromosome region rearrangements
Chromosome region 4q12 rearrangements are associated with myeloid and lymphoid neoplasms due to disruption of the PDGFRA and/or FGFR1 genes. Patients with rearrangement(s) involving PDGFRA most commonly present with chronic eosinophilic leukemia but also can present as acute myeloid leukemia (AML) and/or T-lymphoblastic leukemia/lymphoma (T-ALL). Patients with FGFR1 involvement have various presentations including AML, T- or B-lymphoblastic leukemia/lymphoma (B-ALL), or a mixed phenotype acute leukemia. Imatinib mesylate (imatinib) is the first-line therapy for patients with abnormalities of PDGFRA, whereas patients with FGFR1 fusions are resistant to this therapy and carry a poor prognosis. PMID: 23489324 Source: Regenstrief LOINC

LP62864-1 FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

LOINC Names Get Info

Fully-Specified Name: Cells.4q12 chromosome region rearrangements/Cells counted:NFr:Pt:Bld/Tiss:Qn:FISH
Long Common Name: Cells.4q12 chromosome region rearrangements/Cells counted in Blood or Tissue by FISH
Short Name: Cells.4q12 rear/Cells cnt NFr Bld/T FISH
Display Name: Cells.4q12 chromosome region rearrangements/Cells counted FISH (Bld/Tiss)
Consumer Name Alpha Get Info: Cells.4q12 chromosome region rearrangements/Cells Counted, Blood or tissue specimen

Part Model Get Info

Component
Cells.4q12 chromosome region rearrangements/Cells counted
LP285251-7
- Analyte
  Cells.4q12 chromosome region rearrangements/Cells counted
  LP285251-7
  - Component Numerator
    Cells.4q12 chromosome region rearrangements
    LP190794-0
    - Component Numerator Core
      Cells.4q12 chromosome region rearrangements
      LP190794-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Cells counted
    LP190810-4
    - Component Denominator Core
      Cells counted
      LP190810-4
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NFr
LP6838-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld/Tiss
LP7061-7
- System Core
  Bld/Tiss
  LP7061-7
- Super System
  NULL
Scale
Qn
LP7753-9
Method
FISH
LP62864-1

Basic Attributes

Class: MOLPATH.REARRANGE
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.61 (MIN)
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Buňky.4q12 přestavba chromozomových oblastí/buňky spočítané:Početní podíl:Časový bod:Krev/tkáň:Kvantitativní:Fluorescenční in situ hybridizace (FISH)
el-GR	Greek (Greece)	Αναδιατάξεις χρωμοσωμικής περιοχής Κύτταρα.4q12/Μετρηθέντα κύτταρα:NFr:Pt:Αίμα/Ιστός:Qn:Φθορίζουσα υβριδοποίηση in situ Synonyms: MOLPATH MOLPATH.REARRANGE NFr Pt Qn Αίμα Αίμα/Ιστός Αναδιατάξεις χρωμοσωμικής περιοχής 4q12 Αναδιατάξεις χρωμοσωμικής περιοχής Κύτταρα.4q12 Ιστός Κύτταρα Μετρηθέντα κύτταρα Περιοχή Φθορίζουσα υβριδοποίηση in situ Χρωμόσωμα Χρωμοσωμική περιοχή
es-ES	Spanish (Spain)	Reordenamiento en la región cromosómica 4q12/Contaje celular:Fracción numérica:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH) Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Células Reordenamientos de la región cromosómica 4q12 / Células contadas:Fracción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR	French (France)	Chromosome région 4q12 réarrangements/cellules comptées:Fraction de nombres:Ponctuel:Sang/Tissu:Numérique:FISH
it-IT	Italian (Italy)	Cellule.Riarrangiamenti della regione cromosomica 4q12/Cellule contate:NFr:Pt:Sangue/Tess:Qn:FISH Synonyms: Frazione numerica Ibridazione in situ fluorescente (FISH) Patologia molecolare Punto nel tempo (episodio) Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL	Dutch (Netherlands)	cellen.4q12-chromosoomgebied translocaties/getelde cellen:getalsfractie:moment:bloed of weefsel:kwantitatief:FISH Synonyms: 4q12-chromosoom gebied translocaties
pl-PL	Polish (Poland)	Komórki.rearanżacja regionu chromosomowego 4q12/zliczone komórki:frakcja liczbowa:punkt w czasie:krew lub tkanka:ilościowy:FISH Synonyms: fluorescencyjna hybrydyzacja in situ Komórki z rearanżacją w regionie 12 długiego ramienia chromosomu 4 Komórki z rearanżacją w regionie 12 długiego ramienia chromosomu 4 w stosunku do zliczonych komórek
tr-TR	Turkish (Turkey)	Hücreler.4q12 Kromozom bölgesi yeniden düzenleme/Hücreler sayılan:SayFr:Zmlı:Kan/Dk:Kant:FISH
zh-CN	Chinese (China)	细胞.4q12 染色体区域重排/已计数的细胞:计数型分数:时间点:全血/组织:定量型:FISH Synonyms: 4q12 染色体区域（染色体部位、染色体区、染色体区带、染色体部）重排 Fluorescent in situ hybridization;荧光原位杂交全血或组织;血液/组织;血液或组织分子病理学.基因重排;分子病理学.重排;分子病理学试验.基因重排;分子病理学试验.重排;分子病理学试验类.重排;基因重排;重排分子病理学;分子病理学试验区;地区;局部可用数量表示的;定量性;数值型;数量型;连续数值型标尺所计数的细胞;计数细胞;所计数细胞;已计数细胞所计数细胞;已计数过细胞;已计数细胞;已计过数细胞数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片染色体二体型+染色体三体型染色体部位;染色体区;染色体区带;染色体部;染色体区域（染色体部位、染色体区、染色体区带、染色体部）细胞.4q12 染色体区域（染色体部位、染色体区、染色体区带、染色体部）重排细胞含量;细胞性;细胞性质;细胞构成;细胞类血;血液

Example Units

Unit	Source
%	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.