Version 2.78

Part Descriptions

LP190800-5   Cells.MYC gene rearrangements
The MYC gene (v-myc avian myelocytomatosis viral oncogene homolog) [HGNC Gene ID:7553] is located on chromosome 8q24.21. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4609] Source: National Center for Biotechnology Information (NCBI) Gene

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
Cells.MYC gene rearrangements/Cells counted
Property
NFr
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
FISH

Additional Names

Short Name
Cells.MYC rear/Cells cnt NFr Bld/T FISH
Display Name
Cells.MYC rearrangements/Cells counted FISH (Bld/Tiss)
Consumer Name Alpha Get Info
Cells.MYC Rearrangements/Cells Counted, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.REARRANGE
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.61
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Reordenamientos del gen MYC/Contaje celular:Fracción numérica:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Células Reordenamientos del gen MYC / Células contadas:Fracción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) MYC gène réarrangements/cellules comptées:Fraction de nombres:Ponctuel:Sang/Tissu:Numérique:FISH
it-IT Italian (Italy) Cellue.riarrangiamenti del gene MYC/Cellule contate:NFr:Pt:Sangue/Tess:Qn:FISH
Synonyms: Frazione numerica Gene MYC Ibridazione in situ fluorescente (FISH) Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti del proto-oncogene MYC Riarrangiamenti gene MYC Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) cellen.MYC-genherschikking/getelde cellen:getalsfractie:moment:bloed of weefsel:kwantitatief:FISH
Synonyms: cellen.MYC gen translocaties MYC gen MYC gentranslocatie
tr-TR Turkish (Turkey) Hücreler.MYC geni yeniden düzenleme/Hücreler sayılan:SayFr:Zmlı:Kan/Dk:Kant:FISH
zh-CN Chinese (China) 细胞.MYC 基因重排/已计数的细胞:计数型分数:时间点:全血/组织:定量型:FISH
Synonyms: Burkitt 淋巴瘤 Burkitts 淋巴瘤 c-MYC Fluorescent in situ hybridization;荧光原位杂交 MYC 原癌基因 MYC 基因重排（重组） v-myc myelocytomatosis viral oncogene homolog (avian);MYC;MRTL;bHLHe39;c-Myc;avian myelocytomatosis viral oncogene homolog;class E basic helix-loop-helix protein 39;myc proto-oncogene protein;myc-related translation/localization regulatory factor;proto-on v-myc 骨髓细胞瘤病毒原癌基因同源基因 v-myc 骨髓细胞瘤病毒原癌基因同源基因（v-myc myelocytomatosis viral oncogene homolog） v-myc 髓细胞瘤病毒原癌基因同源基因 v-myc 髓细胞组织增生病毒原癌基因同源基因 v-myc 髓细胞组织增生症病毒原癌基因同源基因 与骨髓细胞瘤病毒同源的原癌基因 与骨髓细胞瘤病毒同源的原癌基因（Protooncogene homologous to myelocytomatosis virus） 与髓细胞瘤病毒同源的原癌基因 与髓细胞组织增生病毒同源的原癌基因 与髓细胞组织增生症病毒同源的原癌基因 伯基特氏淋巴瘤 伯基特淋巴瘤 全血或组织;血液/组织;血液或组织 分子病理学.基因重排;分子病理学.重排;分子病理学试验.基因重排;分子病理学试验.重排;分子病理学试验类.重排;基因重排;重排 分子病理学;分子病理学试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 所计数的细胞;计数细胞;所计数细胞;已计数细胞 所计数细胞;已计数过细胞;已计数细胞;已计过数细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 细胞.MYC 基因重排（重组） 细胞含量;细胞性;细胞性质;细胞构成;细胞类 血;血液 遗传基因;遗传因子;吉恩;生物基因 骨髓细胞瘤病毒同源原癌基因 髓细胞瘤病毒同源原癌基因 髓细胞组织增生病毒同源原癌基因 髓细胞组织增生症病毒同源原癌基因

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78229-2