Version 2.77

Part Descriptions

LP190805-4   Cells.PDGFRB gene rearrangements
The PDGFRB gene (platelet-derived growth factor receptor, beta polypeptide) [HGNC Gene ID:8804] is located on chromosome 5q33.1. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008] [NCBI Gene ID: 5159] Source: National Center for Biotechnology Information (NCBI) Gene

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
Cells.PDGFRB gene rearrangements/Cells counted
Property
NFr
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
FISH

Additional Names

Short Name
Cells.PDGFRB rear/Cells cnt Bld/T FISH
Display Name
Cells.PDGFRB rearrangements/Cells counted FISH (Bld/Tiss)
Consumer Name Alpha Get Info
Cells.PDGFRB Rearrangements/Cells Counted, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.REARRANGE
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.61
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Reordenamientos del gen PDGFRB/Contaje celular:Fracción numérica:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Células Reordenamientos del gen PDGFRB / Células contadas:Fracción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) PDGFRB gène réarrangements/cellules comptées:Fraction de nombres:Ponctuel:Sang/Tissu:Numérique:FISH
it-IT Italian (Italy) Cellule.riarrangiamenti del gene PDGFRB/Cellule contate:NFr:Pt:Sangue/Tess:Qn:FISH
Synonyms: Frazione numerica Ibridazione in situ fluorescente (FISH) Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti del gene del recettore beta del fa Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) cellen.PDGFRB-genherschikking/getelde cellen:getalsfractie:moment:bloed of weefsel:kwantitatief:FISH
Synonyms: cellen.PDGFRB gen translocaties PDGFRB-gentranslocaties
tr-TR Turkish (Turkey) Hücreler.PDGFRB geni yeniden düzenleme/Hücreler sayılan:SayFr:Zmlı:Kan/Dk:Kant:FISH
zh-CN Chinese (China) 细胞.PDGFRB 基因重排/已计数的细胞:计数型分数:时间点:全血/组织:定量型:FISH
Synonyms: Beta 血小板源性生长因子受体前体 Beta 血小板源性生长因子受体前体（Beta platelet-derived growth factor receptor precursor，PDGFRB） CD140B 基因 Fluorescent in situ hybridization;荧光原位杂交 JTK12 PDGFbetaR PDGFR PDGFR1 PDGFRB 基因重排（重组） PDGF-R-BETA PDGF-R-β PDGFβR β血小板源性生长因子受体前体 全血或组织;血液/组织;血液或组织 分子病理学.基因重排;分子病理学.重排;分子病理学试验.基因重排;分子病理学试验.重排;分子病理学试验类.重排;基因重排;重排 分子病理学;分子病理学试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 所计数的细胞;计数细胞;所计数细胞;已计数细胞 所计数细胞;已计数过细胞;已计数细胞;已计过数细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 细胞.PDGFRB 基因重排（重组） 细胞含量;细胞性;细胞性质;细胞构成;细胞类 血;血液 遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit Source
% Example UCUM Units

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