78235-9

Cells.PDGFRB gene rearrangements/Cells counted in Blood or Tissue by FISH

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Part Descriptions

LP190805-4 Cells.PDGFRB gene rearrangements
The PDGFRB gene (platelet-derived growth factor receptor, beta polypeptide) [HGNC Gene ID:8804] is located on chromosome 5q33.1. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008] [NCBI Gene ID: 5159] Source: National Center for Biotechnology Information (NCBI) Gene

LP62864-1 FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

LOINC Names Get Info

Fully-Specified Name: Cells.PDGFRB gene rearrangements/Cells counted:NFr:Pt:Bld/Tiss:Qn:FISH
Long Common Name: Cells.PDGFRB gene rearrangements/Cells counted in Blood or Tissue by FISH
Short Name: Cells.PDGFRB rear/Cells cnt Bld/T FISH
Display Name: Cells.PDGFRB rearrangements/Cells counted FISH (Bld/Tiss)
Consumer Name Alpha Get Info: Cells.PDGFRB Rearrangements/Cells Counted, Blood or tissue specimen

Part Model Get Info

Component
Cells.PDGFRB gene rearrangements/Cells counted
LP285680-7
- Analyte
  Cells.PDGFRB gene rearrangements/Cells counted
  LP285680-7
  - Component Numerator
    Cells.PDGFRB gene rearrangements
    LP190805-4
    - Component Numerator Core
      Cells.PDGFRB gene rearrangements
      LP190805-4
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Cells counted
    LP190810-4
    - Component Denominator Core
      Cells counted
      LP190810-4
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NFr
LP6838-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld/Tiss
LP7061-7
- System Core
  Bld/Tiss
  LP7061-7
- Super System
  NULL
Scale
Qn
LP7753-9
Method
FISH
LP62864-1

Basic Attributes

Class: MOLPATH.REARRANGE
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.61 (MIN)
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Buňky.gen PDGFRB přestavba/buňky spočítané:Početní podíl:Časový bod:Krev/tkáň:Kvantitativní:Fluorescenční in situ hybridizace (FISH)
el-GR	Greek (Greece)	Κύτταρα.Γονιδιακές αναδιατάξεις PDGFRB/Μετρηθέντα κύτταρα:NFr:Pt:Αίμα/Ιστός:Qn:Φθορίζουσα υβριδοποίηση in situ Synonyms: MOLPATH MOLPATH.REARRANGE NFr Pt Qn Αίμα Αίμα/Ιστός Γονιδιακές αναδιατάξεις PDGFRB Γονίδιο Ιστός Κύτταρα Κύτταρα.Γονιδιακές αναδιατάξεις PDGFRB Μετρηθέντα κύτταρα Φθορίζουσα υβριδοποίηση in situ
es-ES	Spanish (Spain)	Reordenamientos del gen PDGFRB/Contaje celular:Fracción numérica:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH) Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Células Reordenamientos del gen PDGFRB / Células contadas:Fracción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR	French (France)	PDGFRB gène réarrangements/cellules comptées:Fraction de nombres:Ponctuel:Sang/Tissu:Numérique:FISH
it-IT	Italian (Italy)	Cellule.riarrangiamenti del gene PDGFRB/Cellule contate:NFr:Pt:Sangue/Tess:Qn:FISH Synonyms: Frazione numerica Ibridazione in situ fluorescente (FISH) Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti del gene del recettore beta del fa Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL	Dutch (Netherlands)	cellen.PDGFRB-genherschikking/getelde cellen:getalsfractie:moment:bloed of weefsel:kwantitatief:FISH Synonyms: cellen.PDGFRB gen translocaties PDGFRB-gentranslocaties
pl-PL	Polish (Poland)	Komórki.PDGFRB gen rearanżacje/zliczone komórki:frakcja liczbowa:punkt w czasie:krew lub tkanka:ilościowy:FISH Synonyms: fluorescencyjna hybrydyzacja in situ Komórki z rearanżacjami genu PDGFRB Rearanżacje genu PDGFRB
tr-TR	Turkish (Turkey)	Hücreler.PDGFRB geni yeniden düzenleme/Hücreler sayılan:SayFr:Zmlı:Kan/Dk:Kant:FISH
zh-CN	Chinese (China)	细胞.PDGFRB 基因重排/已计数的细胞:计数型分数:时间点:全血/组织:定量型:FISH Synonyms: Beta 血小板源性生长因子受体前体 Beta 血小板源性生长因子受体前体（Beta platelet-derived growth factor receptor precursor，PDGFRB） CD140B 基因 Fluorescent in situ hybridization;荧光原位杂交 JTK12 PDGFbetaR PDGFR PDGFR1 PDGFRB 基因重排（重组） PDGF-R-BETA PDGF-R-β PDGFβR β血小板源性生长因子受体前体全血或组织;血液/组织;血液或组织分子病理学.基因重排;分子病理学.重排;分子病理学试验.基因重排;分子病理学试验.重排;分子病理学试验类.重排;基因重排;重排分子病理学;分子病理学试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺所计数的细胞;计数细胞;所计数细胞;已计数细胞所计数细胞;已计数过细胞;已计数细胞;已计过数细胞数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片细胞.PDGFRB 基因重排（重组）细胞含量;细胞性;细胞性质;细胞构成;细胞类血;血液遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit	Source
%	Example UCUM Units

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.