78245-8
MYB gene deletion [Presence] in Blood or Tissue by FISH
Active
Term Description
This term was created for, but is not limited in use to, the Vysis MYB SpectrumAqua FISH Probe Kit, which is intended to detect deletion of the MYB gene located within the 6q23 chromosome region.
Source: Regenstrief LOINC
Part Descriptions
LP188999-9 MYB gene
Chromosome 6q23 deletion, which involves the MYB gene, is associated with chronic lymphocytic leukemia (CLL), acute lymphoblastic leukemia (ALL), B-cell small lymphocytic lymphoma, non-Hodgkin lymphoma, and multiple myeloma. Approximately 5% of patients with CLL were found to have the 6q23 deletion. PMID: 18949612 Deletion of the MYB gene may play a role in tumorigenesis since it is involved in transcriptional repression.[NCBI Gene ID:4602]
Source: Regenstrief LOINC
LP62864-1 FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues.
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Source: Wikipedia, FISH
Fully-Specified Name
- Component
- MYB gene deletion
- Property
- PrThr
- Time
- Pt
- System
- Bld/Tiss
- Scale
- Ord
- Method
- FISH
Additional Names
- Short Name
- MYB Del Bld/T Ql FISH
- Display Name
- MYB gene del FISH Ql (Bld/Tiss)
- Consumer Name Alpha Get Info
- MYB gene deletion analysis, Blood or tissue specimen
Example Answer List: LL744-4
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- MOLPATH.DEL
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.61
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Gen MYB Deleción: |
| es-MX | Spanish (Mexico) | Deleción del gen MYB: |
| fr-FR | French (France) | MYB gène délétion: |
| it-IT | Italian (Italy) | MYB, gene Delezione: Synonyms: Delezione genetica Gene MYB Ibridazione in situ fluorescente (FISH) Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & |
| nl-NL | Dutch (Netherlands) | MYB-gen deletie: Synonyms: MYB gen |
| tr-TR | Turkish (Turkey) | MYB geni delesyon: Synonyms: Mevcut |
| zh-CN | Chinese (China) | MYB 基因 缺失: Synonyms: Fluorescent in situ hybridization; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright