Version 2.80

Term Description

Trough levels of phenytoin free and total are measured for therapeutic drug management in patients with renal failure or conditions that may alter albumin concentrations.

Part Description

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
78439-7 Phenytoin free and total trough panel - Serum or Plasma
Indent74983-8 Phenytoin Free [Mass/volume] in Serum or Plasma --trough mg/L
Indent74976-2 Phenytoin [Mass/volume] in Serum or Plasma --trough mg/L

Fully-Specified Name

Component
Phenytoin free & total trough panel
Property
-
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Phenytoin free and total trough panel - Serum or Plasma
Short Name
Phyt Free + Total Trough Pnl SerPl
Display Name
Phenytoin free and total trough panel
Consumer Name Alpha Get Info
Free and Total phenytoin Trough panel, Blood

Basic Attributes

Class
PANEL.DRUG/TOX
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54 (ADD)
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Πίνακας ελεύθερης & ελαχίστων επιπέδων ολικής φαινυτοΐνης:-:Pt:Ορός/Πλάσμα:Qn:
Synonyms: Πίνακας ελεύθερης & ελαχίστων επιπέδων ολικής φαινυτοΐνης Φαινυτοΐνη Φαινυτοΐνη.ελεύθερη
es-ES Spanish (Spain) Panel fenitoina total y libre valle:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Panel de canal libre y total de fenitoína:-:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FR French (France) Diphénylhydantoïne libre et totale taux résiduel panel:-:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Fenitoina libera & totale valore minimo, panel Fenitoina libera & totale, panel Fenitoina libera & totale valore minimo, panel Fenitoina libera & totale valore minimo, panel:-:Pt:Siero/Plasma:Qn:
Synonyms: Fenitoina Libera Livelli farmacologici e tossicologia Panel Fenitoina libera e totale valore minimo Plasma Punto nel tempo (episodio) Set di prescrizione per livelli farmacologici e to Siero Siero o Plasma
nl-NL Dutch (Netherlands) fenytoïne vrij & totaal dalspiegel panel:-:moment:serum of plasma:kwantitatief:
tr-TR Turkish (Turkey) Fenitoin serbest ve total en düşük panel:-:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 游离型与总苯妥英波谷组套:-:时间点:血清/血浆:定量型:
Synonyms: C15H12N2O2;二苯乙内酰脲;苯妥营;二苯基乙内酰脲;二苯尿囊素 全体数量 全部 共计 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.药物/毒理学试验;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.药物/毒理学;医嘱组.药物与毒理学;医嘱组.药物与毒理学试验;医嘱组类.药物/毒理学;医嘱组类.药物/毒理学试验;医嘱组类.药物与毒理学;医嘱组类.药物与毒理学试验;实验室医嘱组类.药物/毒理学;实验室医嘱组类.药物/毒理学试验;实验室医嘱组类.药物与毒理学;实验室医嘱组类.药物与毒理学试验;药物与毒理学医嘱组;药物与毒理学医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 总 总和 总数 总量 总额 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 毒品 毒品类 汇总 游离 游离型与总苯妥英（二苯乙内酰脲、二苯基乙内酰脲、二苯尿囊素、苯妥营）波谷（谷值、低谷、最小值、最低点）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 游离型苯妥英;游离苯妥英;苯妥英.游离;苯妥英（二苯乙内酰脲、二苯基乙内酰脲、二苯尿囊素、苯妥营）.游离型 组 组合 组合医嘱 组合类 组套 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 非蛋白结合型 非蛋白质结合型

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78439-7
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/78439-7