Version 2.77

Term Description

This term was created for, but not limited in use to, the Roche cobas Cyclosporine test kit.
Source: Regenstrief LOINC

Part Description

LP16098-3   cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. PMID: 19545653 Source: Regenstrief LOINC, PMID: 19545653

Fully-Specified Name


Additional Names

Short Name
cycloSPORINE Bld IA-sCnc
Display Name
cycloSPORINE IA (Bld) [Moles/Vol]
Consumer Name Alpha Get Info
cycloSPORINE, Blood

Basic Attributes

First Released
Version 2.54
Last Updated
Version 2.66
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Member of these Groups Get Info

LOINC Group Group Name
LG43291-0 Cyclosporine|Pt|Bld|IA
LG2876-3 Cyclosporine|SCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cyclosporin:Stoffmengenkonzentration:Zeitpunkt:Blut:Quantitativ:Immunoassay
Synonyms: Ciclosporin
el-GR Greek (Greece) Κυκλοσπορίνη:Συγκέντρωση ουσίας:Χρονική στιγμή:Αίμα:Ποσοτική:IA
es-ES Spanish (Spain) Ciclosporina:Concentración de sustancia:Punto temporal:Sangre:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) cicloesporino:Concentración de sustancias:Punto temporal:Sangre:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Tsüklosporiin:SCnc:Pt:B:Qn:IA
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Veri
fr-CA French (Canada) Cyclosporine:Concentration de substance:Temps ponctuel:Sang:Quantitatif:IA
fr-FR French (France) Ciclosporine:Moles/Volume:Ponctuel:Sang:Numérique:Immunoanalyse
fr-BE French (Belgium) Cyclosporine:Concentration de substance:Temps ponctuel:Sang:Quantitatif:IA
it-IT Italian (Italy) Ciclosporina:SCnc:Pt:Sangue:Qn:IA
Synonyms: Concentrazione di Sostanza Immunoassay Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) ciclosporine:mol/volume:moment:bloed:kwantitatief:immunoassay
Synonyms: IA
ru-RU Russian (Russian Federation) Циклоспорин:МолКонц:ТчкВрм:Кр:Колич:IA
Synonyms: Количественный Кровь Молярность;Молярная объёмная концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Siklosporin:SubKons:Zmlı:Kan:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 环孢菌素:物质的量浓度:时间点:全血:定量型:免疫测定法
Synonyms: 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 环孢霉素A; 山地明环孢灵; 环孢多肽A; 环孢素; 赛斯平; 环孢菌素; 环孢菌素A; 环孢素A;山地明;环孢多肽;环孢抑制剂;环孢灵;环孢霉素;环孢霉素A;环孢素;Cyclosporine;Cyclosporin; Restasis; Cyclosporine A; cyclosporin A; Antibiotic S 7481F1; 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonameth 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

Unit Source
nmol/L Example UCUM Units

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