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Part Description

LP200136-2   D-3-phosphoglycerate dehydrogenase
D-3-phosphoglycerate dehydrogenase (3-PGDH) is encoded by the PHGDH gene, located on chromosome 1p12, and functions as part of the L-serine biosynthesis pathway to catalyze the conversion of 3-phospho-D-glycerate to 3-phosphohydroxypyruvate. Defects in the PHGDH gene are associated with two disorders: phosphoglycerate dehydrogenase(PGDH) deficiency and Neu-Laxova syndrome 1 (NLS1). PGDH deficiency is associated with congenital microcephaly, psychomotor retardation, and seizures. NLS1 is a lethal, autosomal recessive syndrome associated with ichthyosis, marked intrauterine growth restriction, microcephaly, hypoplastic lungs and central nervous system anomalies. [UniProt: O43175] Antibodies to 3-PGDH are detected in patients with chronic liver diseases, primiarily autoimmune hepatitis (AIH). PMID: 21707887 Source: Regenstrief LOINC, UniProt: O43175

LOINC Names Get Info

Fully-Specified Name
D-3-phosphoglycerate dehydrogenase:CCnt:Pt:Fibroblasts:Qn:
Long Common Name
D-3-phosphoglycerate dehydrogenase [Enzymatic activity/mass] in Fibroblast
Short Name
3-PGDH Fib-cCnt
Display Name
D-3-phosphoglycerate dehydrogenase (Fibroblast) [Catalytic activity/Mass]
Consumer Name Alpha Get Info
D-3-phosphoglycerate dehydrogenase, Fibroblast

Part Model Get Info

  • Component
    D-3-phosphoglycerate dehydrogenase
    LP200136-2
    • Analyte
      D-3-phosphoglycerate dehydrogenase
      LP200136-2
      • Component Numerator
        D-3-phosphoglycerate dehydrogenase
        LP200136-2
        • Component Numerator Core
          D-3-phosphoglycerate dehydrogenase
          LP200136-2
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CCnt
    LP6790-2
  • Time
    Pt
    LP6960-1
  • System
    Fibroblasts
    LP7234-0
    • System Core
      Fibroblasts
      LP7234-0
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)D-3-fosfoglycerátdehydrogenáza:Katalytický obsah:Časový bod:Fibroblast:Kvantitativní:
el-GRGreek (Greece)D-3-φωσφογλυκερική αφυδρογονάση:CCnt:Pt:Ινοβλάστες:Qn:
Synonyms: CCnt CHEM D D-3-φωσφογλυκερική αφυδρογονάση Pt Qn Ινοβλάστες
es-ESSpanish (Spain)D-3-fosfoglicerato deshidrogenasa:Contenido catalítico:Punto temporal:Fibroblastos:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)D-3-fosfoglicerato deshidrogenasa:Contenido catalítico:Punto temporal:Fibroblasto:Cuantitativo:
fr-FRFrench (France)D-3-phosphoglycérate déshydrogénase:Catalytique/Masse:Ponctuel:Fibroblastes:Numérique:
it-ITItalian (Italy)D-3-deidrogenasi fosfoglicerato:CCnt:Pt:Fibroblasti:Qn:
Synonyms: Chimica Contenuto Catalitico Fibroblasto Punto nel tempo (episodio)
nl-NLDutch (Netherlands)D-3-fosfoglyceraat-dehydrogenase:enzymatische activiteit/massa:moment:fibroblast:kwantitatief:
pl-PLPolish (Poland)Dehydrogenaza D-3-fosfoglicerynianowa:zawartość katalityczna:punkt w czasie:fibroblasty:ilościowy:
tr-TRTurkish (Turkey)D-3-fosfogliserat dehidrojenaz:Ktlİçrk:Zmlı:Fibroblastlar:Kant:
zh-CNChinese (China)D-3-磷酸甘油酸脱氢酶:催化含量:时间点:成纤维细胞:定量型:
Synonyms: Ⅲ III Rh;Rhesus;恒河猴;猕猴;罗猴 三 催化含量(单位质量);单位质量的酶单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 去氢酶 叁 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 纤维原细胞;纤维母细胞

Example Units

UnitSource
nmol/min/mg{protein}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78982-6