79254-9

LORazepam cutoff [Mass/volume] in Saliva (oral fluid) for Confirmatory method

Active

Part Descriptions

LP16176-7 LORazepam
Lorazepam (marketed under the brand names Ativan®, Temesta®, Tavor®) is a drug which is a benzodiazepine derivative. Pharmacologically, it is classified as a sedative -hypnotic, anxiolytic and anticonvulsant. Lorazepam reduces anxiety, interferes with new memory formation, reduces agitation, induces sleep, treats seizures, treats nausea and vomiting, and relaxes muscles. Lorazepam is used for the short-term treatment of anxiety, insomnia, acute seizures including status epilepticus, and sedation of hospitalized patients, as well as sedation of aggressive patients. Due to tolerance and dependence, lorazepam is recommended for short-term use, up to two to four weeks only. Among benzodiazepines, lorazepam has possible physical addiction potential. Lorazepam also has misuse potential; the main types of misuse are for recreational purposes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Lorazepam (Wikipedia)

LP16176-7 LORazepam
A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent. Source: National Library of Medicine, MeSH 2006

LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: LORazepam cutoff:MCnc:Pt:Saliva:Qn:Confirm
Long Common Name: LORazepam cutoff [Mass/volume] in Saliva (oral fluid) for Confirmatory method
Short Name: LORazepam CtO Sal Cfm-mCnc
Display Name: LORazepam cutoff Confirm (Sal) [Mass/Vol]
Consumer Name Alpha Get Info: LORazepam cutoff, Saliva

Part Model Get Info

Component
LORazepam cutoff
LP228887-8
- Analyte
  LORazepam cutoff
  LP228887-8
  - Component Numerator
    LORazepam cutoff
    LP228887-8
    - Component Numerator Core
      LORazepam
      LP16176-7
    - Component Numerator Core Suffix
      cutoff
      LP29252-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Saliva
LP7565-7
- System Core
  Saliva
  LP7565-7
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Confirm
LP6197-0

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.54 (ADD)
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Lorazepam mezní hodnota:Hmotnostní koncentrace:Časový bod:Sliny:Kvantitativní:Konfirmace
el-GR	Greek (Greece)	Λοραζεπάμη αποκοπή:MCnc:Pt:Σίελος:Qn:Επιβεβαίωση Synonyms: DRUG/TOX MCnc Pt Qn αποκοπή Επιβεβαίωση Λοραζεπάμη Σίελος
es-ES	Spanish (Spain)	Lorazepam Punto de corte:Concentración de masa:Punto temporal:Saliva:Qn:Confirmatorio Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Límite de LORazepam:Concentración de masa:Punto temporal:Saliva:Cuantitativo:Confirmar
et-EE	Estonian (Estonia)	Lorasepaam otsustuspiir:MCnc:Pt:Sal:Qn:Kinnitav Synonyms: Juhuslik Kvantitatiivne Sülg
fr-CA	French (Canada)	Lorazépam Seuil décisionnel:Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:Confirmation
fr-FR	French (France)	Lorazépam cut off:Masse/Volume:Ponctuel:Salive:Numérique:Confirmation
fr-BE	French (Belgium)	Lorazépam Seuil décisionnel:Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:Confirmé Synonyms: Seuil décisionnel
it-IT	Italian (Italy)	Lorazepam, cutoff:MCnc:Pt:Saliva:Qn:Conferma Synonyms: Concentrazione di Massa Cut-off Livelli farmacologici e tossicologia Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	lorazepam afkapwaarde:massa/volume:moment:speeksel:kwantitatief:bevestiging
ru-RU	Russian (Russian Federation)	Лоразепам порог:МассКонц:ТчкВрм:Слюна:Колич:Подтверждать Synonyms: Количественный Массовая концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Lorazepam kestirim:KütlKons:Zmlı:Tükürük:Kant:Onay Synonyms: Teyid
zh-CN	Chinese (China)	氯羟安定截止点:质量浓度:时间点:唾液:定量型:毒理学确认试验 Synonyms: 劳拉西泮;氯羟去甲安定可用数量表示的;定量性;数值型;数量型;连续数值型标尺截断值;截止;截止值时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 津;津液;涎确认方法;确认法;确认试验药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类

Example Units

Unit	Source
ng/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79254-9

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.