Version 2.80

Part Description

LP19492-5   Thiopurine methyltransferase
Thiopurine methyltransferase (TPMT) is an enzyme that catalyzes the S-methylation of thiopurine drugs including 6-mercatptopurine, thioguanine, and azathioprine (AZA). These drugs are used to treat acute lymphoblastic leukemia, inflammatory bowel disease, rheumatoid arthritis, and organ transplant rejection. Patients with low or absent TPMT activity are at increased risk for toxicity due to increased accumulation of unmetabolised drug. Information from Current Clinical Pharmacology. 2006;1:119-128. Source: Regenstrief Institute

Fully-Specified Name

Component
Thiopurine methyltransferase
Property
CSub
Time
Pt
System
RBC
Scale
Qn
Method

Additional Names

Long Common Name
Thiopurine methyltransferase [Enzymatic activity/substance] in Red Blood Cells
Short Name
TPMT cSub RBC
Display Name
Thiopurine methyltransferase (RBC) [Catalytic activity/Moles]
Consumer Name Alpha Get Info
Thiopurine methyltransferase, Red blood cells

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Μεθυλοτρανσφεράση θειοπουρίνης:CSub:Pt:Ερυθρά αιμοσφαίρια:Qn:
Synonyms: CSub Μεθυλοτρανσφεράση θειοπουρίνης
es-ES Spanish (Spain) Tiopurina metiltransferasa:CSub:Punto temporal:Glóbulos rojos:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Tiopurina metiltransferasa:Sustancia catalítica:Punto temporal:Eritrocitos:Cuantitativo:
fr-FR French (France) Thiopurine méthyltransférase:Substance catalytique:Ponctuel:Érythrocytes:Numérique:
it-IT Italian (Italy) Tiopurina metiltransferasi:CSub:Pt:RBC:Qn:
Synonyms: Chimica Globuli rossi Punto nel tempo (episodio) Sostanza catalitica
nl-NL Dutch (Netherlands) thiopurinemethyltransferase:enzymatische activiteit/mol:moment:erytrocyten:kwantitatief:
Synonyms: rode bloedcellen
ru-RU Russian (Russian Federation) Тиопурин метилтрансфераза:КаталВещ:ТчкВрм:Эритроциты:Колич:
Synonyms: Каталитическое вещество;Катализатор Количественный Тиопурин-S-метилтрансфераза Точка во времени;Момент
tr-TR Turkish (Turkey) Tiyopürin metiltransferaz:KtlSub:Zmlı:Eritrosit:Kant:
Synonyms: RBC
zh-CN Chinese (China) 硫嘌呤甲基转移酶:单位物质的量相对型催化活性:时间点:红细胞:定量型:
Synonyms: Catalytic substance;Csub;酶相对浓度;单位摩尔相对型催化活性;单位克分子相对型催化活性;催化性物质;催化性化学物质 RBC;RBCS;红血球;红血细胞;赤血球 TPMT;巯嘌呤甲基转移酶 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 转甲基酶

Example Units

Unit Source
umol/h/mmol{Hb} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79468-5