7960-8

Leptospira interrogans Ab [Units/volume] in Serum by Hemagglutination

Active

Part Descriptions

LP17129-5   Leptospira interrogans
A genus of question mark-shaped bacteria spirochetes which is found in fresh water that is contaminated by animal urine. It causes LEPTOSPIROSIS. Source: National Library of Medicine, MeSH 2006

LP17129-5   Leptospira interrogans
Leptospira is a flexible, spiral-shaped, Gram-negative spirochete with internal flagella. Leptospira interrogans has many serovars based on cell surface antigens. Most leptospirosis infections initially present with an acute onset of fever, headache and muscle pain, which symptoms last about a week. The three organ systems most frequently involved with more significant illness are the central nervous system, kidneys, and liver, and jaundice occurs with severe infections. With the appearance of antileptospiral antibodies, the acute phase of the disease subsides and leptospires can no longer be isolated from the blood. The disease is usually biphasic, with the acute phase followed by an immune phase, which occurs after an asymptomatic period of several days. The immune phase is associated with fever and central nervous system involvement, specifically meningitis. Leptospires appear in the urine during this phase and are shed for various periods depending on the host. Severe leptospirosis is associated with progressive impairment of hepatic and renal function, and renal failure is the most common cause of death.
Leptospirosis is a worldwide zoonosis with a variety of animal hosts. The primary reservoir is wild animals such as rodents, which can shed leptospires throughout their lifetimes. Domestic animals are also an important source of human infections. The disease is more widespread in tropical countries. Direct or indirect contact with urine containing virulent leptospires is the major means by which leptospirosis is transmitted.
Leptospira species, which include L. interrogans, L. autumnalis, L. borgpetersenii, and L. weili are further divided into more than 200 serotypes based on their antigenic composition. The more severe form of leptospirosis is frequently associated with the icterohaemorrhagiae serotype and is often referred to as Weil's disease. [NCBI Books: NBK8451] Source: Regenstrief LOINC, NCBI Books: NBK8451

Fully-Specified Name

Component

Leptospira interrogans Ab

Property

ACnc

Time

Pt

System

Ser

Scale

Qn

Method

HA

Additional Names

Short Name

L inter Ab Ser HA-aCnc

Display Name

L. interrogans Ab HA Qn (S)

Consumer Name Alpha Get Info

Leptospira interrogans antibody, Blood

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 1.0h(2)

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

14431

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Arbitrary concentration
• Autoantibodies
• Autoantibody
• Hemagglutination
• ID
• IHA
• Infectious Disease
• InfectiousDisease
• L inter
• L interrogans
• Leptospirosis
• Microbiology
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Serum
• SR

Example Units

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.