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Part Description

LP201662-6   L-serine
L-serine (L-ser) is an amino acid that plays a central role in cellular proliferation and is the major source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. L-ser is converted to D-ser by serine racemase. Altered CNS D-ser levels have been associated with a variety of neurologic conditions, including schizophrenia and Parkinson's disease. L-ser also plays a specific role in the CNS, and patients with defects of L-ser synthesis have significant neurological impairment. Two enzyme defects linked to L-ser synthesis have been discovered: 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency and phosphoserine phosphatase (PSP) deficiency. Patients with 3-PGDH deficiency can have significant neurologic impairment, including congenital microcephaly and seizures associated with decreased white matter volume and myelination, and L-ser supplementation has been used to treat the seizures in this patient population. PSP deficiency has only been identified in one patient, whose symptoms also improved with L-ser treatment. PMID: 12534373 Source: Regenstrief LOINC,

LOINC Names Get Info

Fully-Specified Name
L-serine:SCnc:Pt:CSF:Qn:
Long Common Name
L-serine [Moles/volume] in Cerebrospinal Fluid
Short Name
L-serine CSF-sCnc
Display Name
L-serine (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
L-serine, Spinal fluid

Part Model Get Info

  • Component
    L-serine
    LP201662-6
    • Analyte
      L-serine
      LP201662-6
      • Component Numerator
        L-serine
        LP201662-6
        • Component Numerator Core
          L-serine
          LP201662-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.83 (MIN)
Change Reason
Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
79586-4R- and S-beta aminoisobutyrate and D- and L-serine panel - Cerebrospinal Fluid

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)L-serin:Látková koncentrace:Časový bod:Mozkomíšní mok:Kvantitativní:
el-GRGreek (Greece)L-σερίνη:SCnc:Pt:ΕΝΥ:Qn:
Synonyms: CHEM L-σερίνη Pt Qn SCnc ΕΝΥ Σερίνη
es-ESSpanish (Spain)L-serina:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)L-serina:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-FRFrench (France)L-sérine:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
it-ITItalian (Italy)L-serina:SCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio)
nl-NLDutch (Netherlands)L-serine:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
pl-PLPolish (Poland)L-seryna:stężenie molowe:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy:
tr-TRTurkish (Turkey)L-serin:SubKons:Zmlı:BOS:Kant:
zh-CNChinese (China)L-丝氨酸:物质的量浓度:时间点:脑脊液:定量型:
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Ser 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 左 左侧 左侧（Left，L） 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

Example Units

UnitSource
umol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79601-1