79608-6
2-Methyltyrosine [Moles/volume] in Serum or Plasma
Active
Part Description
LP201655-0 2-Methyltyrosine
Metyrosine is only found in individuals that have used or taken this drug. It is an inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)Metyrosine inhibits tyrosine hydroxylase, which catalyzes the first transformation in catecholamine biosynthesis, i.e., the conversion of tyrosine to dihydroxyphenylalanine (DOPA). Because the first step is also the rate-limiting step, blockade of tyrosine hydroxylase activity results in decreased endogenous levels of catecholamines and their synthesis. This consequently, depletes the levels of the catecholamines dopamine, adrenaline and noradrenaline in the body,usually measured as decreased urinary excretion of catecholamines and their metabolites. One main end result of the catecholamine depletion is a decrease in blood presure.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
Metyrosine
LOINC Names Get Info
- Fully-Specified Name
- 2-Methyltyrosine:
SCnc: Pt: Ser/Plas: Qn: - Long Common Name
- 2-Methyltyrosine [Moles/volume] in Serum or Plasma
- Short Name
- 2Me-tyrosine SerPl-sCnc
- Display Name
- 2-Methyltyrosine [Moles/Vol]
- Consumer Name Alpha Get Info
- 2-Methyltyrosine, Blood
Part Model Get Info
- Component
- 2-Methyltyrosine
LP201655-0
- Analyte
- 2-Methyltyrosine
LP201655-0
- Component Numerator
- 2-Methyltyrosine
LP201655-0
- Component Numerator Core
- 2-Methyltyrosine
LP201655-0
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- SCnc
LP6860-3
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser/Plas
LP7576-4
- System Core
- Ser/Plas
LP7576-4
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | 2-methyltyrosin: |
| el-GR | Greek (Greece) | 2-μεθυλοτυροσίνη: Synonyms: 2-μεθυλοτυροσίνη CHEM Pt Qn SCnc Ορός Ορός/Πλάσμα Πλάσμα |
| es-MX | Spanish (Mexico) | 2-metiltirosina: |
| es-ES | Spanish (Spain) | 2-Metiltirosina: Synonyms: Cuantitativo |
| fr-FR | French (France) | 2-méthyl-tyrosine: |
| it-IT | Italian (Italy) | 2-Metiltirosina: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | 2-methyltyrosine: |
| pl-PL | Polish (Poland) | 2-Metylotyrozyna: |
| tr-TR | Turkish (Turkey) | 2-Metiltirozin: |
| zh-CN | Chinese (China) | 2-甲基酪氨酸: Synonyms: Ⅱ II 克分子浓度; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://