79619-3

S-beta aminoisobutyrate/Creatinine [Molar ratio] in Urine

Active

Part Descriptions

LP201653-5 S-beta aminoisobutyrate
Beta aminoisobutyric acid (BAIB) is a nonprotein amino acid that is an end product of pyrimidine metabolism. The R and S enantiomers (previously named D-(minus)-BAIB and L-plus-BAIB) are produced from thymine and L-valine, respectively. Under normal circumstances, urine contains predominantly R-BAIB (from thymine) because it is eliminated by filtration and tubular secretion, while plasma contains about 80% S-BAIB (from valine), which is reabsorbed in the kidneys. In patients with dihydropyrimidine dehydrogenase deficiency, thymine catabolism is decreased, which results in moderately decreased CSF concentration and markedly decreased plasma concentration of BAIB. On the other hand, urine BAIB is elevated despite decreased breakdown of thymine, which indicates that there must be cross-over in the thymine and valine degradation pathways. PMID: 14705962 Deficiency of D-beta-aminoisobutyrate:pyruvate aminotransferase (EC 2.6.1.40) , an enzyme that is involved in the catabolism R-BAIB, also results in elevated urine BAIB and is associated with hyperuricemia. [OMIM: 210100] Source: Regenstrief LOINC, PMID: 14705962

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LOINC Names Get Info

Fully-Specified Name: S-beta aminoisobutyrate/Creatinine:SRto:Pt:Urine:Qn:
Long Common Name: S-beta aminoisobutyrate/Creatinine [Molar ratio] in Urine
Short Name: S-B-AIB/Creat Ur-sRto
Display Name: S-beta aminoisobutyrate/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info: S-beta aminoisobutyrate/Creatinine, Urine

Part Model Get Info

Component
S-beta aminoisobutyrate/Creatinine
LP287008-9
- Analyte
  S-beta aminoisobutyrate/Creatinine
  LP287008-9
  - Component Numerator
    S-beta aminoisobutyrate
    LP201653-5
    - Component Numerator Core
      S-beta aminoisobutyrate
      LP201653-5
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Creatinine
    LP32035-5
    - Component Denominator Core
      Creatinine
      LP32035-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.56 (MIN)
Change Reason: Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
79605-2	R- and S-beta aminoisobutyrate and D- and L-serine panel - Urine

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	S-beta-aminoizobutyrát/kreatinin:Látkový poměr:Časový bod:Moč:Kvantitativní:
el-GR	Greek (Greece)	S-β-αμινοϊσοβουτυρικό/Κρεατινίνη:SRto:Pt:Ούρα:Qn: Synonyms: CHEM Pt Qn S SRto S-β-αμινοϊσοβουτυρικό β-αμινοϊσοβουτυρικό Κρεατινίνη Ούρα
es-ES	Spanish (Spain)	S-beta aminoisobutirato/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	S-beta aminoisobutirato / creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-FR	French (France)	S-bêta aminoisobutyrate/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
it-IT	Italian (Italy)	S-Beta aminoisobutirrato/Creatinina:Srto:Pt:Urine:Qn: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza
nl-NL	Dutch (Netherlands)	S-bèta-aminoisobutyraat/creatinine:molaire verhouding:moment:urine:kwantitatief: Synonyms: kreatinine
pl-PL	Polish (Poland)	S-beta aminoizomaślan/kreatynina:współczynnik molowy:punkt w czasie:mocz:ilościowy:
tr-TR	Turkish (Turkey)	S-beta aminoizobütirat/Kreatinin:SOrn:Zmlı:İdrar:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	S-beta 氨基异丁酸/肌酐:物质的量比率:时间点:尿液:定量型: Synonyms: 3-氨基异丁酸;B-AIB;Beta-氨基异丁酸;β氨基异丁酸;β-氨基异丁酸 B CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 S 型 S-β氨基异丁酸;S-β-氨基异丁酸;S-B-AIB UCr β 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐时刻;随机;随意;瞬间物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值肌酸内酰胺贝塔

Example Units

Unit	Source
umol/mmol{creat}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.