79638-3
Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate pattern [Interpretation] in Serum or Plasma Narrative
Active
Part Description
LP201667-5 Beta alanine & Beta aminoisobutyrate & Gamma aminobutyrate pattern
Changes in the CSF, plasma and urine levels of beta alanine, beta aminoisobutyrate (BAIB) and gamma aminobutyrate (GABA) may help identify certain metabolic disorders. Beta alanine is a structural analogue of GABA and may also function as a neurotransmitter since it is both a glycine and GABAA receptor agonist. Dihydropyrimidine dehydrogenase (DPD) is the first enzyme in the pyrimidine degradation pathway, in which uracil and thymine are catabolized to beta alanine and R-BAIB, respectively. The S enantiomer of BAIB (S-BAIB) is derived from valine catabolism. Under normal circumstances, urine contains predominantly R-BAIB (from thymine) because it is eliminated by filtration and tubular secretion, while plasma contains about 80% S-BAIB (from valine), which is reabsorbed in the kidneys. In patients with a DPD deficiency, uracil and thymine catabolism is decreased. This results in mildly decreased plasma and urine concentrations and normal CSF concentration of beta alanine, and moderately decreased CSF concentration and markedly decreased plasma concentration of BAIB. On the other hand, urine BAIB is elevated, which indicates that there must be cross-over in the thymine and valine degradation pathways. PMID: 14705962
Source: Regenstrief LOINC, PMID: 14705962
Fully-Specified Name
- Component
- Beta alanine & Beta aminoisobutyrate & Gamma aminobutyrate pattern
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nar
- Method
Additional Names
- Short Name
- B-Alanine + B-AIB + GABA patt SerPl-Imp
- Display Name
- Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate pattern Nar [Interp]
- Consumer Name Alpha Get Info
- Interpretation of Beta alanine and beta aminoisobutyrate and Gamma aminobutyrate pattern test result, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.58
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79650-8 | Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Patrón de Beta alanina y Beta aminoisobutirato y Gamma aminobutirato: |
| es-MX | Spanish (Mexico) | Patrón de beta alanina y beta aminoisobutirato y gamma aminobutirato: |
| fr-FR | French (France) | Bêta alanine et bêta aminoisobutyrate et gamma aminoisobutyrate Profil: |
| it-IT | Italian (Italy) | Beta alanina & Beta aminoisobutirrato & Gamma aminoisobutirrato, profilo: Synonyms: Chimica Impressione/interpretazione di studio Plasma Profilo di Beta alanina & |
| nl-NL | Dutch (Netherlands) | bèta-alanine & bèta-aminoisobutyraat & gamma-aminobutyraat patroon: Synonyms: beta alanine & |
| tr-TR | Turkish (Turkey) | Beta alanin ve Beta aminoizobütirat ve Gamma aminobutirat örüntüsü: Synonyms: Beta alanin ve Beta aminoizobütirat ve Gamma aminobutirat paterni |
| zh-CN | Chinese (China) | Beta 丙氨酸与 Beta 氨基异丁酸与 Gamma 氨基丁酸模式: Synonyms: 3-氨基异丁酸; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=79638-3
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright