Version 2.80

Part Descriptions

LP201662-6   L-serine
L-serine (L-ser) is an amino acid that plays a central role in cellular proliferation and is the major source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. L-ser is converted to D-ser by serine racemase. Altered CNS D-ser levels have been associated with a variety of neurologic conditions, including schizophrenia and Parkinson's disease. L-ser also plays a specific role in the CNS, and patients with defects of L-ser synthesis have significant neurological impairment. Two enzyme defects linked to L-ser synthesis have been discovered: 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency and phosphoserine phosphatase (PSP) deficiency. Patients with 3-PGDH deficiency can have significant neurologic impairment, including congenital microcephaly and seizures associated with decreased white matter volume and myelination, and L-ser supplementation has been used to treat the seizures in this patient population. PSP deficiency has only been identified in one patient, whose symptoms also improved with L-ser treatment. PMID: 12534373 Source: Regenstrief LOINC ,

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database , Creatinine

Fully-Specified Name

Component
L-serine/Creatinine
Property
SRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Long Common Name
L-serine/Creatinine [Molar ratio] in Urine
Short Name
L-serine/Creat Ur-sRto
Display Name
L-serine/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info
L-serine/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56 (MIN)
Change Reason
Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
79605-2 R- and S-beta aminoisobutyrate and D- and L-serine panel - Urine

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) L-σερίνη/Κρεατινίνη:SRto:Pt:Ούρα:Qn:
Synonyms: L-σερίνη SRto Κρεατινίνη Σερίνη
es-ES Spanish (Spain) L-serina/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) L-serina / creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-FR French (France) L-sérine/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
it-IT Italian (Italy) L-serina/Creatinina:Srto:Pt:Urine:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza
nl-NL Dutch (Netherlands) L-serine/creatinine:molaire verhouding:moment:urine:kwantitatief:
Synonyms: kreatinine
tr-TR Turkish (Turkey) L-serin/Kreatinin:SOrn:Zmlı:İdrar:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) L-丝氨酸/肌酐:物质的量比率:时间点:尿液:定量型:
Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 Ser UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 左 左侧 左侧（Left，L） 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 肌酸内酰胺

Example Units

Unit Source
umol/mmol{creat} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79645-8