Version 2.80

Part Descriptions

LP30736-0   Homocysteine cysteine disulfide
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Homocystine and homocysteine-cysteine mixed disulfide account for >98% of total homocysteine in plasma from healthy individuals. PMID: 11592966 Oxidation of low-density lipoprotein (LDL) is thought to be a major factor in the pathophysiology of atherosclerosis. Elevated plasma homocysteine is an accepted risk factor for atherosclerosis, and may act through LDL oxidation, although this is controversial. However, the major thiol in plasma is cysteine, which is present at concentrations approximately 10 times greater than homocysteine; therefore homocystine in plasma is insignificant, and consequently homocystine is unlikely to influence LDL oxidation in vivo. PMID: 14732479 Increasing evidence supports a role for an elevation of homocysteine in schizophrenia. It has been demonstrated that neural tube defects are related to a genetic defect in homocysteine metabolism. Sufficient intake of folic acid is believed to reduce this risk by enhancing methylation of homocysteine and its conversion to methionine, thereby compensating for this genetic defect. Plasma homocysteine levels are elevated when folate levels are in the lower half of the normal range. PMID: 16143442 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database ,

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database , Creatinine

Fully-Specified Name

Component
Homocysteine cysteine disulfide/Creatinine
Property
SRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Long Common Name
Homocysteine cysteine disulfide/Creatinine [Molar ratio] in Urine
Short Name
Hycs-Cys diS/Creat Ur-sRto
Display Name
Homocysteine cysteine disulfide/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info
Homocysteine cysteine disulfide/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56 (MIN)
Change Reason
Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Δισουλφιδικός δεσμός κυστεΐνης-ομοκυστεΐνης/Κρεατινίνη:SRto:Pt:Ούρα:Qn:
Synonyms: SRto Δισουλφιδικός δεσμός κυστεΐνης-ομοκυστεΐνης Κρεατινίνη Κυστεΐνη Ομοκυστεΐνη
es-ES Spanish (Spain) Homocisteína cisteína disulfuro/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Disulfuro de cisteína de homocisteína / creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-CA French (Canada) Bisulfure de cystéine homocystéine/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
fr-FR French (France) Homocystéine cystéine disulfide/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
fr-BE French (Belgium) Bisulfure de cystéine homocystéine/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
it-IT Italian (Italy) Omocisteina cisteina, disolfuro/Creatinina:Srto:Pt:Urine:Qn:
Synonyms: Chimica Disolfuro omocisteina cisteina Punto nel tempo (episodio) Rapporto di sostanza
nl-NL Dutch (Netherlands) homocysteïne cysteïne disulfide/creatinine:molaire verhouding:moment:urine:kwantitatief:
Synonyms: kreatinine
ru-RU Russian (Russian Federation) Гомоцистеин цистеин дисульфид/Креатинин:МольОтн:ТчкВрм:Моча:Колич:
Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR Turkish (Turkey) Homosistein sistein disülfür/Kreatinin:SOrn:Zmlı:İdrar:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) 同型半胱氨酸-半胱氨酸二硫化物/肌酐:物质的量比率:时间点:尿液:定量型:
Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 Cys;巯基丙氨酸 HCY;Hcys;Hcyst;巯基丁氨酸;高半胱氨酸 Hcys-Cys diS;Hcys-Cys 二硫化物;巯基丁氨酸-巯基丙氨酸二硫化物 UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 肌酸内酰胺

Example Units

Unit Source
umol/mmol{creat} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79649-0