Version 2.78

Part Description

LP201693-1   Cytidine
Cytidine is a nucleoside that is composed of the base cytosine linked to the five-carbon sugar D-ribose. Cytidine is a pyrimidine that besides being incorporated into nucleic acids, can serve as substrate for the salvage pathway of pyrimidine nucleotide synthesis; as precursor of the cytidine triphosphate (CTP) needed in the phosphatidylcholine (PC) and phosphatidylethanolamine (PE) biosynthetic pathway. These variations probably reflect the species differences in cytidine deaminase, the enzyme that converts cytidine to uridine in the body. The transports of cytidine into the brain's extracellular fluid, and then into neurons and glia, are essential prerequisites for cytidine to be utilized in brain. An efficient mechanism mediating the brain uptake of circulating cytidine has not yet been demonstrated. The biosynthesis of PC, the most abundant phosphatide in the brain, via the Kennedy pathway requires phosphocholine and cytidine triphosphate (CTP), a cytidine nucleotide, which is involved in the rate-limiting step. The enzyme that converts CTP to endogenous CDP-choline (CTP: phosphocholine cytidylyltransferase) is unsaturated at physiological brain CTP levels. APOBEC is a family of enzymes has been discovered with the ability to deaminate cytidines on RNA or DNA. The human apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G (APOBEC3G, or hA3G) protein, provides cells with an intracellular antiretroviral activity that is associated with the hypermutation of viral DNA through cytidine deamination. Indeed, hA3G belongs to a family of vertebrate proteins that contain one or two copies of a signature sequence motif unique to cytidine deaminases (CTDAs). PMID: 16769123 PMID: 15780864 PMID: 16720547 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database,

Fully-Specified Name

Component
Cytidine
Property
SCnc
Time
Pt
System
CSF
Scale
Qn
Method

Additional Names

Short Name
Cytidine CSF-sCnc
Display Name
Cytidine (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
Cytidine, Spinal fluid

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56
Change Reason
Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
79668-0 Purine and Pyrimidine panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Citidina:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Citidina:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-FR French (France) Cytidine:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
it-IT Italian (Italy) Citidina:SCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) cytidine:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
pl-PL Polish (Poland) Cytydyna:stężenie molowe:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy:
tr-TR Turkish (Turkey) Stidin:SubKons:Zmlı:BOS:Kant:
zh-CN Chinese (China) 胞嘧啶核苷:物质的量浓度:时间点:脑脊液:定量型:
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 胞苷;胞啶;胞甙 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

Example Units

Unit Source
umol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79671-4