79687-0
2,8-dihydroxyadenine/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP201704-6 2,8-dihydroxyadenine
2,8 dihydroxyadenine (DHA) is formed from adenine and elevated levels of DHA are associated with adenine phosphoribosyl transferase (APRT) deficiency, a rare metabolic disorder. Typically adenine is metabolized by ART, but when ART is deficient, adenine is converted to DHA by another enzyme, xanthine dehydrogenase. DHA is cleared by the kidney and excreted in urine, but because it is insoluble in urine, it precipitates as crystals that can aggregate and form kidney stones. DHA crystals can also precipitate within the renal tubules and interstitium and cause severe renal damage. PMID: 26380104
Source: Regenstrief LOINC,
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- 2,8-Dihydroxyadenine/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- 2,8-dihydroxyadenine/Creat Ur-sRto
- Display Name
- 2,8-dihydroxyadenine/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- 2,8-dihydroxyadenine/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56
- Change Reason
- Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
79673-0 | Purine and Pyrimidine panel - Urine |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | 2,8-dihidroxiadenina/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 2,8-dihidroxiadenina / creatinina: |
fr-FR | French (France) | 2,8-dihydroxyadénine/créatinine: |
it-IT | Italian (Italy) | 2,8-diidrossiadenina/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
nl-NL | Dutch (Netherlands) | 2,8-dihydroxyadenine/creatinine: Synonyms: kreatinine |
tr-TR | Turkish (Turkey) | 2,8-dihidroksiadenin/Kreatinin: Synonyms: SubsOranı |
zh-CN | Chinese (China) | 2,8-二羟基腺嘌呤/肌酐: Synonyms: 2,8-双羟基腺嘌呤; |
Example Units
Unit | Source |
---|---|
umol/mmol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=79687-0
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright