80543-2

Norclozapine [Mass/volume] in DBS

Active

Term Description

Dried blood spot (DBS) specimens have been used for therapeutic drug monitoring (TDM) across several classes of drugs including antimicrobials, anticonvulsants and immunosuppressants. DBS specimens are useful for TDM in infants and children due to the small sample volume required. DBS specimens are also useful for outpatient TDM in adults who have been trained to collect their own DBS because most analytes are relatively stable in DBS and the DBS card does not require specialized transportation. PMID: 25204403

Part Description

LP18081-7 Norclozapine
Norclozapine (desmethyl-clozapine),a major metabolite of clozapine, is pharmacologically active. The cytochrome P450 isoenzyme 1A2 is primarily responsible for clozapine metabolism, but 2C, 2D6, 2E1 and 3A3/4 appear to play roles as well. Agents which induce (e.g. cigarette smoke) or inhibit (e.g. theophylline, ciprofloxacin, fluvoxamine) CYP1A2 may increase or decrease, respectively, the metabolism of clozapine. For example, the induction of metabolism caused by smoking means that smokers require up to double the dose of clozapine compared with non-smokers to achieve an equivalent plasma concentration. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Norclozapine

LOINC Names Get Info

Fully-Specified Name: Norclozapine:MCnc:Pt:Bld.dot:Qn:
Long Common Name: Norclozapine [Mass/volume] in DBS
Short Name: Norclozapine DBS-mCnc
Display Name: Norclozapine (DBS) [Mass/Vol]
Consumer Name Alpha Get Info: Norclozapine, Dried blood spot

Part Model Get Info

Component
Norclozapine
LP18081-7
- Analyte
  Norclozapine
  LP18081-7
  - Component Numerator
    Norclozapine
    LP18081-7
    - Component Numerator Core
      Norclozapine
      LP18081-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld.dot
LP21304-8
- System Core
  Bld.dot
  LP21304-8
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.61 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Norklozapin:Hmotnostní koncentrace:Časový bod:Suchá krevní kapka (DBS):Kvantitativní:
el-GR	Greek (Greece)	Νορκλοζαπίνη:MCnc:Pt:Bld.dot:Qn: Synonyms: Bld.dot DRUG/TOX MCnc Pt Qn Αίμα Νορκλοζαπίνη
es-ES	Spanish (Spain)	Norclozapina:Concentración de masa:Punto temporal:gota de sangre (papel de filtro):Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Norclozapina:Concentración de masa:Punto temporal:DBS:Cuantitativo:
et-EE	Estonian (Estonia)	Norklosapiin:MCnc:Pt:Vereplekk:Qn: Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA	French (Canada)	Norclozapine:Concentration de masse:Temps ponctuel:Sang sur papier filtre:Quantitatif:
fr-FR	French (France)	Norclozapine:Masse/Volume:Ponctuel:Sang buvard:Numérique:
fr-BE	French (Belgium)	Norclozapine:Concentration de masse:Temps ponctuel:Sang sur papier filtre:Quantitatif:
it-IT	Italian (Italy)	Norclozapina:MCnc:Pt:Sangue.su carta da filtro:Qn: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue Spot sangue secco
nl-NL	Dutch (Netherlands)	norclozapine:massa/volume:moment:gedroogde bloedspot:kwantitatief:
ru-RU	Russian (Russian Federation)	Норклозапин:МассКонц:ТчкВрм:Кр.Сух.капл:Колич: Synonyms: Количественный Кровь Кровь сухая капля Массовая концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Norklozapin:KütlKons:Zmlı:Kan.nokta:Kant:
zh-CN	Chinese (China)	去甲基氯氮平:质量浓度:时间点:全血.斑点:定量型: Synonyms: 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 脱甲基氯氮平;去甲基氯扎平;去甲氯扎平;去甲氯氮平;氯扎平代谢产物;氯氮平代谢产物药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血;血液

Example Units

Unit	Source
ug/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.