80617-4
Cefuroxime free [Mass/volume] in Serum or Plasma
Active
Part Descriptions
LP206596-1 Cefuroxime.free
Cefuroxime (brand names Ceftin, Zinacef, Supacef) is a broad-spectrum cephalosporin antibiotic resistant to beta-lactamase and used to treat infections caused by gram-negative and gram-positive organisms. Free cefuroxime is the non-protein bound form of cefuroxime in the blood. Bound cefuroxime constitutes 33 to 50% of circulating cefuroxime. PMID: 2393271 Cefuroxime levels are measured for therapeutic drug monitoring and to avoid toxicity. Blood levels of cefuroxime can be reduced by dialysis.
Source: Regenstrief LOINC
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Cefuroxime.free:
MCnc: Pt: Ser/Plas: Qn: - Long Common Name
- Cefuroxime free [Mass/volume] in Serum or Plasma
- Short Name
- Cefuroxime.free SerPl-mCnc
- Display Name
- Cefuroxime free [Mass/Vol]
- Consumer Name Alpha Get Info
- Free cefuroxime, Blood
Part Model Get Info
- Component
- Cefuroxime.free
LP206596-1
- Analyte
- Cefuroxime.free
LP206596-1
- Component Numerator
- Cefuroxime.free
LP206596-1
- Component Numerator Core
- Cefuroxime.free
LP206596-1
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- MCnc
LP6827-2
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser/Plas
LP7576-4
- System Core
- Ser/Plas
LP7576-4
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.56 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Cefuroxim volný: |
| el-GR | Greek (Greece) | Κεφουροξίμη.ελεύθερη: Synonyms: DRUG/TOX MCnc Pt Qn Κεφουροξίμη Κεφουροξίμη.ελεύθερη Ορός Ορός/Πλάσμα Πλάσμα |
| es-ES | Spanish (Spain) | Cefuroxima libre: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Cefuroxima libre: |
| fr-FR | French (France) | Céfuroxime libre: |
| it-IT | Italian (Italy) | Ceftriaxone.libero: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | cefuroxime.vrij: |
| zh-CN | Chinese (China) | 头孢呋辛.游离型: Synonyms: 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://