Clostridioides difficile toxin A+B tcdA+tcdB genes [Presence] in Stool by NAA with probe detection
Qualitative detection of nucleic acid sequences in the Clostridium difficile toxin A (tcdA) and B (tcdB) genes in stool specimens by real-time PCR methods. This assay does not differentiate between C. difficile toxin A and B genes. This term was created for, but not limited in use to, the submitter's test kit, xTAG® Gastrointestinal Pathogen Panel (GPP).
Source: Regenstrief LOINC
LP204848-8 Clostridioides difficile toxin A+B tcdA+tcdB genes
Clostridium difficile toxin's A and B are encoded by the tcdA and tcdB genes, respectively. PMID: 20664812 They share similar molecular characteristics with comparable sizes (308 kD for tcdA and 269 for tcdB) and 63% homology in their amino acid sequences. PMID: 9312171 TcdA and tcdB are expressed in response to environmental stresses, such as antibiotics.[ PMID 15831824] Nucleic acid sequences within these genes are targeted to confirm the presence of C. difficile toxins and diagnose the cause of diarrhea, abdominal pain, fever, nausea and other toxin-producing symptoms. Source: Regenstrief LOINC
- Clostridioides difficile toxin A+B tcdA+tcdB genes
- Short Name
- C dif tox tcdA+tcdB Stl Ql NAA+probe
- Display Name
- C. difficile toxin A+B tcdA+tcdB genes NAA+probe Ql (Stl)
- Consumer Name Alpha Get Info
- Clostridioides difficile toxin A+B tcdA+tcdB genes, Stool
Example Answer List: LL360-9Source: Regenstrief Institute
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
- First Released
- Version 2.56
- Last Updated
- Version 2.73
- Change Reason
- Removed parentheses around the gene names in the Component based on the current LOINC model; Updated genus name from Clostridium to Clostridioides based on current (2019) accepted nomenclature for this genus [PMID:27370902].
- Order vs. Observation
- Common Test Rank Get Info
Member of these Panels
|LOINC||Long Common Name|
|95183-0||Clostridioides difficile toxin and BI-NAP1-027 strain DNA panel - Stool by NAA with probe detection|
|79381-0||Gastrointestinal pathogens panel - Stool by NAA with probe detection|
Language Variants Get Info
|de-DE||German (Germany)||Clostridioides difficile Toxine A+B tcdA+tcdB-Gene:
|de-AT||German (Austria)||Synonyms: Clostridium difficile bin. Toxin-Gene /ST ql. PCR|
|es-ES||Spanish (Spain)||Gen de la toxina del Clostridium difficile A+B (tcdA+tcdB):
|es-MX||Spanish (Mexico)||Toxina de Clostridioides difficile A + B genes tcdA + tcdB:
|fr-FR||French (France)||Clostridioides difficile toxines A+B tcdA+tcdB gènes:
|it-IT||Italian (Italy)||Clostridium Difficile (tcdA+tcdB), geni tossine A+B:
Synonyms: Geni delle tossine A+B del Clostridium Difficile ( Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Tossina A di Clostridium difficile Tossina A+B di Clostridium difficile Tossina di Clostridium difficile
|nl-NL||Dutch (Netherlands)||Clostridioides difficile toxine A+B (tcdA+tcdB) genen:
Synonyms: Clostridium difficile Clostridium difficile toxine Clostridium difficile toxine A Clostridium difficile toxine A+B Clostridium difficile toxine A+B (tcdA+tcdB) genen ontlasting;
|zh-CN||Chinese (China)||艰难梭菌毒素 A+B tcdA+tcdB 基因:
Synonyms: A 型 A,B 型;
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