Version 2.77

Term Description

Qualitative detection of nucleic acid sequences in the Clostridium difficile toxin A (tcdA) and B (tcdB) genes in stool specimens by real-time PCR methods. This assay does not differentiate between C. difficile toxin A and B genes. This term was created for, but not limited in use to, the submitter's test kit, xTAG® Gastrointestinal Pathogen Panel (GPP).
Source: Regenstrief LOINC

Part Description

LP204848-8   Clostridioides difficile toxin A+B tcdA+tcdB genes
Clostridium difficile toxin's A and B are encoded by the tcdA and tcdB genes, respectively. PMID: 20664812 They share similar molecular characteristics with comparable sizes (308 kD for tcdA and 269 for tcdB) and 63% homology in their amino acid sequences. PMID: 9312171 TcdA and tcdB are expressed in response to environmental stresses, such as antibiotics.[ PMID 15831824] Nucleic acid sequences within these genes are targeted to confirm the presence of C. difficile toxins and diagnose the cause of diarrhea, abdominal pain, fever, nausea and other toxin-producing symptoms. Source: Regenstrief LOINC

Fully-Specified Name

Clostridioides difficile toxin A+B tcdA+tcdB genes

Additional Names

Short Name
C dif tox tcdA+tcdB Stl Ql NAA+probe
Display Name
C. difficile toxin A+B tcdA+tcdB genes NAA+probe Ql (Stl)
Consumer Name Alpha Get Info
Clostridioides difficile toxin A+B tcdA+tcdB genes, Stool

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.56
Last Updated
Version 2.73
Change Reason
Removed parentheses around the gene names in the Component based on the current LOINC model; Updated genus name from Clostridium to Clostridioides based on current (2019) accepted nomenclature for this genus [PMID:27370902].
Order vs. Observation
Common Test Rank Get Info

Member of these Panels

LOINC Long Common Name
95183-0 Clostridioides difficile toxin and BI-NAP1-027 strain DNA panel - Stool by NAA with probe detection
79381-0 Gastrointestinal pathogens panel - Stool by NAA with probe detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Clostridioides difficile Toxine A+B tcdA+tcdB-Gene:Nachweis oder Schwellenwert:Zeitpunkt:Stuhl:Ordinal:Zielfragmentamplifikation mit Sondendetektion
de-AT German (Austria) Synonyms: Clostridium difficile bin. Toxin-Gene /ST ql. PCR
es-ES Spanish (Spain) Gen de la toxina del Clostridium difficile A+B (tcdA+tcdB):PrThr:Punto temporal:Heces:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Toxina de Clostridioides difficile A + B genes tcdA + tcdB:Presencia o umbral:Punto temporal:Heces:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Clostridioides difficile toxines A+B tcdA+tcdB gènes:Présence/Seuil:Ponctuel:Selle:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Clostridium Difficile (tcdA+tcdB), geni tossine A+B:PrThr:Pt:Feci:Ord:Sonda.amp.tar
Synonyms: Geni delle tossine A+B del Clostridium Difficile ( Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Tossina A di Clostridium difficile Tossina A+B di Clostridium difficile Tossina di Clostridium difficile
nl-NL Dutch (Netherlands) Clostridioides difficile toxine A+B (tcdA+tcdB) genen:aanwezigheid:moment:feces:ordinaal:probe-detectie
Synonyms: Clostridium difficile Clostridium difficile toxine Clostridium difficile toxine A Clostridium difficile toxine A+B Clostridium difficile toxine A+B (tcdA+tcdB) genen ontlasting; feces probe.amp.tar
zh-CN Chinese (China) 艰难梭菌毒素 A+B tcdA+tcdB 基因:存在情况或阈值:时间点:大便:序数型:探针法.基因扩增.靶向
Synonyms: A 型 A,B 型;AB 型 B 型 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 便;大肠运动;排便;粪便;肠运动 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分子病理学 - 基因类 基因 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针 艰难梭状芽胞杆菌;艰难芽孢梭菌 艰难梭状芽胞杆菌毒素 A;艰难梭状芽胞杆菌毒素 A 型;艰难梭菌毒素 A 型;艰难芽孢梭菌毒素 A;艰难芽孢梭菌毒素 A 型 艰难梭状芽胞杆菌毒素 A+B;艰难梭状芽胞杆菌毒素 A+B 型;艰难梭菌毒素 A+B 型;艰难芽孢梭菌毒素 A+B;艰难芽孢梭菌毒素 A+B 型 艰难梭状芽胞杆菌毒素;艰难芽孢梭菌毒素 艰难梭菌毒素(艰难梭状芽胞杆菌、艰难芽孢梭菌) A+B tcdA+tcdB 基因

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